Cell culture matrix

Abstract

In order to solve the problems of bad microenvironment construction, poor antibacterial effects and poor cell culture effects caused by easy degradation of existing cell culture matrixes, a cell culture matrix that can completely simulate growth environment in cells and has antibacterial and degradation inhibition functions can be developed. The cell culture matrix includes a mixed powder matrix material, a matrix degradation inhibitor and a cationic antibacterial material; the mixed powder matrix material consists of 60-80 wt% of type I collagen, 10-30 wt% of an acellular small intestinal submucosal matrix and 5-10 wt% of an acellular amniotic matrix; the content of the matrix degradation inhibitor is 0.01-1.5 wt% that of the mixed powder matrix material; and the content of the cationic antibacterial material is 0.01-1.5 wt% that of the mixed powder matrix material.

Description

technical field [0001] The invention relates to the field of biological materials, in particular to a cell culture substrate. Background technique [0002] Cell culture technology has been widely used in scientific research, production and clinical application, and is playing an increasingly important role. In cell culture, in addition to precise requirements for culture containers, medium, temperature, dissolved oxygen, and PH, etc., there are actually higher requirements for cell culture substrate carriers that support the adherent growth of cells, because it will directly affect the quality of cell culture. As a result, it plays a key role in obtaining excellent scientific research, production and clinical application effects. [0003] Traditional cell culture substrate materials mainly include natural, synthetic and semi-synthetic materials. Natural materials are currently the main research objects due to their good cell compatibility. In recent years, people mainly u...

AI Technical Summary

Problems solved by technology

[0005] The invention solves the problem of poor cell culture effect caused by poor microenvironment construction, poor antibacterial effect, and easy degradation of the existing cell culture substrate, and develops a product that can more completely simulate the growth environment in the cell body while having antibacterial and degradation inhibiting properties. Functional Cell Culture Substrate

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