Traditional Chinese medicine antipruritic spray and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and specifically relates to a traditional Chinese medicine antipruritic spray and a preparation method thereof. The antipruritic spray takes atractylodes rhizome, peppermint, manchurian wildginger, dahurian angelica root, white mulberry root-bark, dried ginger, clove, macleaya cordata, herba eupatorii, mulberry leaf, pericarpium zanthoxyli, Chinese arborvitae twig and leaf and illicium anisatum as main medicinal ingredients. Effective constituents can be extracted by respectively adopting alcohol and vinegar stains, so that medicine effects can be enhanced; 75% alcohol is contained in the substrate and can promote skins to absorb the effective constituents after spraying, so that symptoms can be rapidly relieved, and the regeneration of cell tissue can be accelerated; the used white vinegar contains various organic acids, so that cuticle renewal can be accelerated, the peeling of skin melanin canbe promoted, pores can be tightened, and the regeneration of damaged skins can be promoted; and the spray can reduce the irritation of hormone drugs on the skins and is significant in effect.

Description

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine antipruritic spray and a preparation method thereof. Background technique

[0002] Pruritus, a skin sensation that evokes the desire to scratch, is a common symptom of pruritus localized and neurodermatitis. The active ingredients of traditional antipruritics are mostly capsaicin, anesthetics, calcineurin inhibitors, glucocorticoids, cannabinoids, doxepin, and prostate inhibitors.

[0003] Capsaicin plays an antipruritic effect by acting on TRPV1 and depleting substance P. It can be used to treat localized itching, especially neurogenic itching such as paresthesia back pain, brachioradialis itching and postherpetic neuralgia. It can also be used for nodules Prurigo, aquagenic pruritus, psoriasis, and uremic pruritus.

[0004] Topical local anesthetics such as 1% pramoxine cream, 2.5% to 5% lidocaine an...

Examples

Embodiment 1

[0053] Embodiment 1: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials: 25 parts of Atractylodes atractylodes, 25 parts of Peppermint, 8 parts of Asarum, 15 parts of Angelica dahurica, and 15 parts of Cortex Mori , 8 parts of dried ginger, 15 parts of cloves, 8 parts of Boluohui, 15 parts of Peilan, 15 parts of mulberry leaves, 8 parts of Sichuan pepper, 15 parts of oriental cypress leaves, and 8 parts of mangcao.

[0054] Preparation process: Grind Atractylodes atractylodis, Mint, Angelica dahurica, Clove, Perrin, Asarum, Dried Ginger, Mulberry Leaf, Morus Alba Bark, Arborvitae Leaf, Boluohui, Shujiao, and Mangcao to 50 meshes respectively; if the crushed particles are too fine, During extraction, the medicinal powder is easily wrapped into a mass by the solvent, and it is difficult to dissolve the active ingredient. If the crushed particle is too coarse, the contact area betwee...

Embodiment 2

[0062] Embodiment 2: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials, 20 parts of Atractylodes atractylodes, 30 parts of Mint, 5 parts of Asarum, 20 parts of Angelica dahurica, and 20 parts of Cortex Mori , 10 parts of dried ginger, 10 parts of cloves, 10 parts of Boluohui, 20 parts of Peilan, 20 parts of mulberry leaves, 10 parts of Sichuan pepper, 10 parts of arborvitae leaves, and 5 parts of mangcao.

[0063] Preparation process: Atractylodes atractylodis, peppermint, Angelica dahurica, clove, Peilan, Asarum, dried ginger, mulberry leaves, Morus alba, Arborvitae leaves, Boluohui, Shujiao, and Mangcao were crushed to 40 meshes.

[0064] Weigh Atractylodes Rhizoma Atractylodis, Peppermint, Angelica dahurica, Clove, Perrin, Asarum and Ginger powder according to the proportion, mix them evenly as medicine powder I, put it in a glass container, add 75% ethanol solution 8 times th...

Embodiment 3

[0071] Embodiment 3: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials: 30 parts of Atractylodes atractylodes, 20 parts of Peppermint, 10 parts of Asarum, 10 parts of Angelica dahurica, and 10 parts of Cortex Mori , 5 parts of dried ginger, 20 parts of cloves, 5 parts of Boluohui, 10 parts of Peilan, 10 parts of mulberry leaves, 5 parts of Sichuan pepper, 20 parts of oriental cypress leaves, and 20 parts of mangcao.

[0072] Preparation process: Atractylodes atractylodis, peppermint, Angelica dahurica, clove, Peilan, Asarum, dried ginger, mulberry leaves, Morus alba, Arborvitae leaves, Boluohui, Shujiao, and Mangcao were crushed to 60 meshes.

[0073] Weigh Atractylodes Rhizoma Atractylodis, Peppermint, Angelica, Clove, Perrin, Asarum, and Ginger powder according to the proportion, mix them evenly as medicinal powder I, put them in a glass container, add 75% ethanol solution 9 ti...

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine antipruritic spray and a preparation method thereof. Background technique

[0002] Pruritus, a skin sensation that evokes the desire to scratch, is a common symptom of pruritus localized and neurodermatitis. The active ingredients of traditional antipruritics are mostly capsaicin, anesthetics, calcineurin inhibitors, glucocorticoids, cannabinoids, doxepin, and prostate inhibitors.

[0003] Capsaicin plays an antipruritic effect by acting on TRPV1 and depleting substance P. It can be used to treat localized itching, especially neurogenic itching such as paresthesia back pain, brachioradialis itching and postherpetic neuralgia. It can also be used for nodules Prurigo, aquagenic pruritus, psoriasis, and uremic pruritus.

[0004] Topical local anesthetics such as 1% pramoxine cream, 2.5% to 5% lidocaine an...

Examples

Embodiment 1

[0053] Embodiment 1: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials: 25 parts of Atractylodes atractylodes, 25 parts of Peppermint, 8 parts of Asarum, 15 parts of Angelica dahurica, and 15 parts of Cortex Mori , 8 parts of dried ginger, 15 parts of cloves, 8 parts of Boluohui, 15 parts of Peilan, 15 parts of mulberry leaves, 8 parts of Sichuan pepper, 15 parts of oriental cypress leaves, and 8 parts of mangcao.

[0054] Preparation process: Grind Atractylodes atractylodis, Mint, Angelica dahurica, Clove, Perrin, Asarum, Dried Ginger, Mulberry Leaf, Morus Alba Bark, Arborvitae Leaf, Boluohui, Shujiao, and Mangcao to 50 meshes respectively; if the crushed particles are too fine, During extraction, the medicinal powder is easily wrapped into a mass by the solvent, and it is difficult to dissolve the active ingredient. If the crushed particle is too coarse, the contact area betwee...

Embodiment 2

[0062] Embodiment 2: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials, 20 parts of Atractylodes atractylodes, 30 parts of Mint, 5 parts of Asarum, 20 parts of Angelica dahurica, and 20 parts of Cortex Mori , 10 parts of dried ginger, 10 parts of cloves, 10 parts of Boluohui, 20 parts of Peilan, 20 parts of mulberry leaves, 10 parts of Sichuan pepper, 10 parts of arborvitae leaves, and 5 parts of mangcao.

[0063] Preparation process: Atractylodes atractylodis, peppermint, Angelica dahurica, clove, Peilan, Asarum, dried ginger, mulberry leaves, Morus alba, Arborvitae leaves, Boluohui, Shujiao, and Mangcao were crushed to 40 meshes.

[0064] Weigh Atractylodes Rhizoma Atractylodis, Peppermint, Angelica dahurica, Clove, Perrin, Asarum and Ginger powder according to the proportion, mix them evenly as medicine powder I, put it in a glass container, add 75% ethanol solution 8 times th...

Embodiment 3

[0071] Embodiment 3: This embodiment provides a traditional Chinese medicine antipruritic spray, which is made of the following traditional Chinese medicine raw materials: 30 parts of Atractylodes atractylodes, 20 parts of Peppermint, 10 parts of Asarum, 10 parts of Angelica dahurica, and 10 parts of Cortex Mori , 5 parts of dried ginger, 20 parts of cloves, 5 parts of Boluohui, 10 parts of Peilan, 10 parts of mulberry leaves, 5 parts of Sichuan pepper, 20 parts of oriental cypress leaves, and 20 parts of mangcao.

[0072] Preparation process: Atractylodes atractylodis, peppermint, Angelica dahurica, clove, Peilan, Asarum, dried ginger, mulberry leaves, Morus alba, Arborvitae leaves, Boluohui, Shujiao, and Mangcao were crushed to 60 meshes.

[0073] Weigh Atractylodes Rhizoma Atractylodis, Peppermint, Angelica, Clove, Perrin, Asarum, and Ginger powder according to the proportion, mix them evenly as medicinal powder I, put them in a glass container, add 75% ethanol solution 9 ti...

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