InDel primer for identifying radish leaf shapes and application of InDel primer
A radish leaf and radish technology, applied in the field of InDel primers for identifying radish leaf shape, can solve the problems of complex regulation mechanism, incomplete dominance or recessiveness, etc.
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Embodiment 1
[0043] Constructing parental BC using Maer radish from southern China (slab leaves, no splits, early bolting) and Nienenzi from Japan (flower leaves, full splits, late bolting) 1 (89 and 87 strains) and F 2 population (183 strains).
[0044] They were sown in the farm of Beijing Vegetable Research Center in 2016, and the results of the survey of leaf rosette stage traits showed that F 1 Plants exhibited fully cleaved leaves (see figure 1 ), F 2 In the segregation population, there were 131 plants and 52 plants of floral leaf (full cleavage, AA or Aa) and plate leaf (no cleavage, aa), respectively, and the segregation ratio was 3:1 (χ 2 =1.14, P=0.286). in bc 1 -P 1 All in the group showed mosaic (AA or Aa), in BC 1 -P 2 The separation ratio of flower leaves (Aa) and plate leaves (aa) in the population is 1:1 (χ 2 =0.01, P=0.915, see Table 1).
[0045] Table 1 Generational population shape observations
[0046]
[0047] The results showed that the leaf shape trait...
Embodiment 2
[0049] IlluminaHiseq 2500 sequencing platform was used to re-sequence the whole genome of the parents "Ma Er" and "Niannianzi", and the polymorphisms of the parents were detected using the 'Aokubi DH' as the reference genome. By GATK software analysis, approximately 534,000 InDel variants were detected between the parents. According to the reference genome information, design a pair of InDel markers every 300-800kb, and consider the distribution on the scaffold as much as possible. 500 pairs of InDel markers were preliminarily designed. The principles of primer design included the annealing temperature at 58-60°C, the base difference between the parents at 3-8 bp, and the size of the amplified fragment at 100-200 bp.
[0050] 626 pairs of EST-SSR markers and 500 pairs of InDel markers were used to detect the polymorphism between the parents "Ma'er" and "Niannianzi", among which 34 pairs of EST-SSR primers and 97 pairs of InDel primers were polymorphic between the parents Sex,...
Embodiment 3
[0052] According to the results of preliminary positioning, further use of F 2 The large population (1656 strains) was fine-mapped, and the InDel32 and SSR80 mapping intervals were located at the R07:25,100,327-25,490,368 position of the "XYB36-2" reference genome. In the interval, 49 InDel markers (InDel548-InDel596) were designed at intervals of 50-100 Kb based on parental genome data, and a locally encrypted linkage map was constructed (see image 3 ). Genetic linkage analysis located the radish leaf shape gene LS in the 45kb interval between Indel593 (R07:25,182,138) and Indel594 (R07:25,227,193) (see image 3 ).
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