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Tremella spore polysaccharide capsule medicament and preparation method thereof

A technology of tremella spore sugar and capsules, which is applied in the field of tremella spore sugar capsules and its preparation, can solve the problems of inconvenient syrup quantification, reduction of the efficacy of tremella spore sugar soft capsules, and easy moisture absorption and deterioration of hard capsules, so as to improve the health of the body. Immune function, anti-radiation damage body immune function, effect of improving drug efficacy

Pending Publication Date: 2020-11-13
JILIN JISHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The liquid culture method has the characteristics of large production scale, high output, short cycle, and easy industrialization. Tremella is generally in the shape of a chrysanthemum or a cockscomb, with a diameter of 5-10 cm. It is soft and white, translucent, and elastic. Tremella is a traditional food in my country. Fungus has always been a favorite food of the people, and the active ingredient in it - tremella polysaccharide has special health care functions, such as the preparation process of tremella spore sugar soft capsule, the invention patent with the publication number CN101439056A A method was designed to solve the problem that the active substance tremella spore sugar made of hard capsules is easy to absorb moisture and deteriorate, and it also solves the problem of inconvenient quantification of syrup. The processing method and composition ratio of the substance can keep the content in a homogeneous state for a long time, but the preparation process of the existing tremella spore sugar soft capsules is too simple and crude, and the polysaccharides in the tremella spore sugar can not be fully brought out, thereby reducing the quality of the tremella spore sugar soft capsules. efficacy of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: a tremella spore sugar capsule medicament and preparation method thereof, raw material composition comprises: tremella fungus, glucose and corn steep liquor dry powder, the preparation method of tremella spore sugar capsule medicament is realized by the following steps:

[0031] Step 1: Spread the Tremella fungus spore liquid evenly on the pre-prepared slant, and culture it in a constant temperature room at 28°C for 5-7 days; ℃, rotation speed 220-240rpm, shaking culture for 60-72h, according to each qualified seed shaker mother bottle corresponds to a seed shaker bottle, insert the seed shaker mother bottle into the medium of the seed shaker bottle one by one, put Constant temperature refrigerated shaker, at 28°C, rotating speed 100-150rpm, shaking culture for 48-60h;

[0032] Step 2: Weigh 2.4kg of glucose and 0.96kg of corn steep liquor dry powder as the first group, weigh 40kg of glucose and 24kg of corn steep liquor dry powder as the second group;

...

Embodiment 2

[0043] Embodiment 2: a tremella spore sugar capsule medicament and preparation method thereof, raw material composition comprises: tremella fungus, glucose and corn steep liquor dry powder, the preparation method of tremella spore sugar capsule medicament is realized by the following steps:

[0044] Step 1: Spread the Tremella fungus spore liquid evenly on the pre-prepared slant, and culture it in a constant temperature room at 28°C for 5-7 days; ℃, rotation speed 220-240rpm, shaking culture for 60-72h, according to each qualified seed shaker mother bottle corresponds to a seed shaker bottle, insert the seed shaker mother bottle into the medium of the seed shaker bottle one by one, put Constant temperature refrigerated shaker, at 28°C, rotating speed 100-150rpm, shaking culture for 48-60h;

[0045] Step 2: Weigh 2.5kg of glucose and 0.97kg of corn steep liquor dry powder as the first group, weigh 45kg of glucose and 25kg of corn steep liquor dry powder as the second group;

...

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Abstract

The invention discloses a tremella spore polysaccharide capsule medicament and a preparation method thereof and relates to the technical field of tremella spore polysaccharide. The tremella spore polysaccharide capsule preparation is prepared from tremella bacteria, glucose and corn steep liquor dry powder. The preparation method of the tremella spore polysaccharide capsule preparation is realizedby the following steps: step 1: uniformly smearing a pre-prepared slope with A tremella bacteria spore liquid, and culturing in a 28 DEG C constant temperature room for 5-7 days; transferring into aseed shake flask mother flask culture medium; placing a constant-temperature freezing oscillator, conducting shake cultivation for 60-72 h under the condition that the temperature is 28 DEG C and therotating speed is 220-240rpm; tremella fuciformis bacteria are propagated and fermented through the seed tank and the fermentation tank, then tremella spore polysaccharideis are purified through the processes of concentration, alcohol precipitation, centrifugation and vacuum drying, so that the medicine effect of the tremella spore polysaccharide capsule is maximized, the medicine effect of the tremella fuciforis spore polysaccharide capsule is improved, and then tremella spore polysaccharide is filled into capsules and packaged to obtain a finished product which can be stored for a long time.

Description

technical field [0001] The invention relates to the technical field of tremella spore sugar, in particular to a tremella spore sugar capsule medicament and a preparation method thereof. Background technique [0002] Tremella is the fruiting body of Basidiomycota, Tremella, Tremella, Tremellaceae, Tremella, also known as Tremella, Tremella, Tremella, etc. It is an edible fungus with high edible and medicinal value. Studies in recent years have shown that Tremella polysaccharides present in Tremella spores and fruiting bodies are acidic heteropolysaccharides, which have the functions of improving immunity, anti-aging, and inhibiting tumor synthesis. It has many medicinal functions, such as promoting the synthesis of protein and nucleic acid, promoting the production of interferon, etc., and belongs to functional oligosaccharides. The cultivation of tremella has a history of more than 100 years in my country, but it has the disadvantages of long cycle, low yield, uneven ears, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/715A61K36/07A61K47/36A61K47/46A61P1/16A61P7/00A61P35/00A61P37/04C08B37/00
CPCA61K31/715A61K36/07A61K9/4858A61K9/4875A61P37/04A61P7/00A61P1/16A61P35/00C08B37/0003A61K2236/19
Inventor 张云金春东王有智于灜波姜晶杨健
Owner JILIN JISHENG PHARMA
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