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Preparation method and application of traditional Chinese medicine ointment for treating eczema

A technology of traditional Chinese medicine and ointment, which is applied in the field of preparation of traditional Chinese medicine ointment, which can solve the problems of loss and incomplete extraction of active ingredients, and achieve the effects of good stability, high drug effective concentration and stable product

Inactive Publication Date: 2020-11-17
武汉润禾生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The main components of Artemisia argyi are volatile oils, flavonoids, and other water-insoluble components. In traditional products, the medicinal materials themselves or water extracts are used directly, and the active ingredients are not completely extracted, or the loss is great during the extraction process.

Method used

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  • Preparation method and application of traditional Chinese medicine ointment for treating eczema
  • Preparation method and application of traditional Chinese medicine ointment for treating eczema
  • Preparation method and application of traditional Chinese medicine ointment for treating eczema

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] The difference in the curative effect of the traditional Chinese medicine ointment prepared by the present invention and other reference substances on eczema:

[0053] A kind of traditional Chinese medicine ointment for the treatment of eczema is prepared by the following method:

[0054] The main active ingredients of the described Chinese medicine ointment are proportioned by weight: Atractylodes lancea (Thunb.) DC 4.0, Lonicera japonica Thunb vine 4.0, Artemisia argyi LevL.etVant. (Uncaria rhynchophylla) 2.0, Paederia scandens 4.0, Liquidambar formosana Hance 2.0.

[0055] Step 1: After removing impurities and dust from the above-mentioned proportions of Atractylodes, Honeysuckle, Artemisia argyi, Uncaria chinensis, and Passepartout, add them into a Chinese medicine extraction tank.

[0056] Step 2: Add water with 2 times the weight of the medicinal materials into the extraction tank, stir and mix well;

[0057] Step 3: the extraction tank is heated to 100°C, sligh...

Embodiment 2

[0106] A traditional Chinese medicine ointment for treating eczema, prepared by the following method:

[0107] The main active ingredients of the traditional Chinese medicine ointment are proportioned by weight: Atractylodes lancea (Thunb.) DC 3.0, Lonicera japonica Thunb vine 3.0, Artemisia argyi LevL.etVant. (Uncaria rhynchophylla) 2.0, Paederia scandens (Paederia scandens) 4.5, Passepartout (Liquidambar formosana Hance) 2.0.

[0108] The preparation steps and parameters are the same as the preparation steps of the sample to be tested in Example 1, and the use method is the same as in Example 1.

[0109] Test results: The changes of eczema after 7 days of use by 20 people are shown in the table below:

[0110]

[0111]

[0112] Example 2 The control substance was used in 4 groups of 20 volunteers, with an age distribution of 6 months to 58 years, including 7 cases of 6-12 months, 10 cases of 2-10 years old, and 3 cases of 10-60 years old. Calculated according to the ...

Embodiment 3

[0114] A traditional Chinese medicine ointment for treating eczema, prepared by the following method:

[0115] The main active ingredients of the traditional Chinese medicine ointment are proportioned by weight: Atractylodes lancea (Thunb.) DC 5.0, Lonicera japonica Thunb vine 5.0, Artemisia argyi LevL.etVant. leaf 5.0, Uncaria (Uncaria rhynchophylla) 1.0, Paederia scandens (Paederia scandens) 5.0, Passepartout (Liquidambar formosana Hance) 1.0.

[0116] The preparation steps and parameters are the same as the preparation steps of the sample to be tested in Example 1, and the use method is the same as in Example 1.

[0117] Test results: The changes of eczema after 7 days of use by 20 people are shown in the table below:

[0118]

[0119] Example 3 There are 20 volunteers in the 4 groups of reference substances, with an age distribution of 6 months to 44 years, including 7 cases of 6-12 months, 10 cases of 2-10 years old, and 3 cases of 10-60 years old. Calculated accordi...

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Abstract

The invention belongs to the field of medicines, and particularly relates to a preparation method and application of a traditional Chinese medicine ointment for treating eczema. Six traditional Chinese medicinal materials including rhizoma atractylodis, honeysuckle stem, folium artemisiae argyi, Chinese fevervine herb, uncaria rhynchophylla and liquidambar formosana hance are combined, and an optimal medicinal material proportion is selected to play a synergistic role; volatile components are collected through steam distillation, then 65%-70% ethyl alcohol is used for extraction, effective components of the traditional Chinese medicinal materials in a prescription can be extracted, and the problems that in a traditional method that water is used for decocting, fumigating and washing, the concentration of the effective components is low, and extraction and dissolution are incomplete are solved; and an extract is prepared by decompressing the extract with 65%-70% ethyl alcohol as a solvent, on the basis, the traditional process is adopted, the ointment is prepared from the extract and other auxiliary materials, and the prepared ointment is good in stability, high in effective drug concentration and definite in curative effect.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a preparation method and application of a traditional Chinese medicine ointment for treating eczema Background technique [0002] Eczema is a skin inflammatory reaction with obvious exudation tendency caused by various internal and external factors. Traditional Chinese medicine calls it "soaking sores", and those that occur in infants are called "milk tinea"; those with acute exudation are called "wet tinea"; [0003] Traditional Chinese medicine believes that eczema is mostly caused by the combination of wind, dampness and heat on the skin, and dampness is the root of the disease. Traditional Chinese medicine attributes the pathogenesis of eczema to insufficient congenital endowment, that is, the patient has an allergic constitution and has acquired a lack of recuperation. The patient's diet is irregular, fat, sweet and thick, or tobacco, alcohol and strong tea damage his ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K9/06A61P17/00A61P17/04A61P29/00A61P31/02A61P31/12A61P37/08
CPCA61K9/0014A61K9/06A61K36/185A61K36/282A61K36/284A61K36/355A61K36/74A61K47/06A61K2236/333A61K2236/37A61P17/00A61P17/04A61P29/00A61P31/02A61P31/12A61P37/08A61K2300/00
Inventor 王线周清郑和国
Owner 武汉润禾生物医药有限公司