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Use of radix glycyrrhizae in treatment of diseases associated with intestinal flora disorder

A technology of intestinal flora and licorice, applied to nervous system diseases, medical preparations containing active ingredients, antibacterial drugs, etc., can solve problems such as licorice disclosure

Pending Publication Date: 2020-11-24
ZHUHAI QLWEL BIO TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, none of the above prior art discloses the specific strains that licorice can regulate intestinal microorganisms. In order to make up for this defect, in the present invention, the inventor has done related research on the regulation of specific strains of licorice

Method used

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  • Use of radix glycyrrhizae in treatment of diseases associated with intestinal flora disorder
  • Use of radix glycyrrhizae in treatment of diseases associated with intestinal flora disorder
  • Use of radix glycyrrhizae in treatment of diseases associated with intestinal flora disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] The preparation of embodiment 1 licorice powder

[0085] The dried licorice rhizome with high medicinal value is selected for preparation, cleaned in cold water, soaked for 2 hours, cut into 2mm slices, and dried in a low-temperature drying oven at a drying temperature of 50°C and a humidity of 10-20%RH , until the surface moisture of the licorice flakes is less than or equal to 0.5%, the dried licorice flakes can be input into a pulverizer while hot for pulverization, and pulverized to 300 meshes to obtain licorice powder.

Embodiment 2

[0086] Embodiment 2 ethanol extraction method prepares Radix Glycyrrhizae extract

[0087] The dried licorice rhizome with high medicinal value is selected for extraction, the dried licorice is dried at 60°C, crushed into a 50-mesh coarse powder, extracted three times with 85% ethanol aqueous solution of 10 times the volume of the dried licorice rhizome, filtered and then reduced. Concentrate under pressure to obtain a concentrated solution, pass the concentrated solution through an adsorption column filled with HPD100, first wash with purified water, remove impurities, and then elute with 65% ethanol aqueous solution, the obtained eluent is concentrated under reduced pressure, decolorized, and refined into leaching paste, and the licorice extract was obtained by vacuum drying.

Embodiment 3

[0088] Embodiment 3 water decoction method prepares licorice extract

[0089]Select the dried licorice rhizome with high medicinal value for extraction, weigh 100g of dried licorice, wash it, put it in a fryer with a suitable volume, add about 600mL of water to immerse the medicinal material for 1h, boil it and heat it for 0.5h. Separate the decoction, decoct the dregs for the second time, mix the decoction with the first decoction, measure the volume with a measuring cylinder, if the volume exceeds 600mL, further boil the decoction and concentrate it to about 600mL to reach the corresponding volume Finally, the decoction liquid is vacuum-packed, packed into 7-8 small bags, and stored at 4°C for later use.

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Abstract

The invention provides use of radix glycyrrhizae or a composition containing radix glycyrrhizae in preparation of medicines, or use of radix glycyrrhizae or the composition containing radix glycyrrhizae in adjustment of intestinal microorganisms. The medicines are medicines for treating diseases associated with intestinal microorganism disorder.

Description

technical field [0001] The invention relates to the technical field of medicine and health care, in particular to the use of licorice or a composition containing licorice in the preparation of medicines, or the use of licorice or a composition containing licorice in regulating intestinal microbes, and the medicine is for the treatment of intestinal Drugs for diseases related to intestinal microbiome disorders. Background technique [0002] A wide variety of microorganisms reside in the human gastrointestinal tract, namely the intestinal flora. The intestinal flora is combined according to a certain ratio, and each bacteria restricts and depends on each other to form an ecological balance in terms of quality and quantity. The normal flora is beneficial and harmless to the human body, and it is necessary. The normal flora is composed of fairly fixed bacteria, which regularly settle in some specific parts of the body and become an integral part of the body. Normal flora not o...

Claims

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Application Information

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IPC IPC(8): A61K36/484A61K45/06A61P1/00A61P31/04A61P31/12A61P33/02A61P25/16A61P25/24A61P35/00
CPCA61K36/484A61K45/06A61P1/00A61P31/04A61P31/12A61P33/02A61P25/16A61P25/24A61P35/00A61K2300/00
Inventor 魏来
Owner ZHUHAI QLWEL BIO TECH LTD