Anti-fatigue microcapsule with slow release effect, preparation method and application

A microcapsule and anti-fatigue technology, which is applied in the direction of microcapsule preparations, medical preparations containing active ingredients, microsphere preparation, etc., can solve the problems of affecting the efficacy, unacceptable, and limiting the amount of addition, so as to improve acceptance, Effect of delayed release and particle size reduction

Pending Publication Date: 2020-11-27
蒋胜
View PDF4 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The raw materials and extracts of American ginseng and rhodiola have a strong bitter taste, which is unacceptable
From the perspective of ordinary food, American ginseng and rhodiola are directl...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Anti-fatigue microcapsule with slow release effect, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) preparation mass fraction is 1% chitosan aqueous solution;

[0034] (2) According to the extract (here, the extract refers to the American ginseng extract and the Rhodiola rosea extract): chitosan mass ratio of 0.5:1, the American ginseng extract and the Rhodiola rosea extract are added to the above-mentioned chitosan solution, and adopt a hand-held high-speed dispersing homogenizer to mix evenly under the rotating speed of 3000rpm / min; the ratio of American ginseng extract and Rhodiola rosea extract can be any ratio. The mass ratio of day extract is 1:1.

[0035] (3) Put the above mixed solution into a syringe, connect the needle and carry out electrostatic spraying at normal temperature to obtain American ginseng and Rhodiola rosea extract-chitosan nanoparticles. The spraying conditions are: flow rate is 0.15mL / h, voltage 20KV, The receiving distance is 8cm.

[0036] (4) Pectin is mixed with sodium alginate in a mass ratio of 5%, and dissolved in water to obtain...

Embodiment 2

[0043] (1) preparation mass fraction is 1.2% chitosan aqueous solution;

[0044] (2) According to the ratio of extract: chitosan mass ratio 0.8:1, American ginseng and Rhodiola rosea extract (mass ratio 1:1) were added to the above chitosan solution, and a hand-held high-speed dispersing homogenizer was used Mix evenly at 3000rpm / min, the ratio of American ginseng and rhodiola extract can be any ratio.

[0045] (3) Put the above-mentioned mixed solution into a syringe, connect the needle and carry out electrostatic spraying at normal temperature to obtain American ginseng and Rhodiola rosea extract-chitosan nanoparticles. The spraying conditions are: flow rate is 0.2mL / h, voltage 22KV, The receiving distance is 10cm.

[0046] (4) Pectin is mixed with sodium alginate in a mass ratio of 20%, and dissolved in water to obtain a sodium alginate-pectin solution with a mass fraction of 1.2%.

[0047](5) take American ginseng and Rhodiola rosea extract-chitosan nanoparticles prepare...

Embodiment 3

[0053] (1) preparation mass fraction is 1.5% chitosan aqueous solution;

[0054] (2) According to the ratio of extract: chitosan mass ratio 1:1, American ginseng and Rhodiola rosea extract (mass ratio 1:1) were added to the above chitosan solution, and a hand-held high-speed dispersing homogenizer was used Mix evenly at 3000rpm / min, the ratio of American ginseng and rhodiola extract can be any ratio.

[0055] (3) Put the above-mentioned mixed solution into a syringe, connect the needle and carry out electrostatic spraying at normal temperature to obtain American ginseng and Rhodiola rosea extract-chitosan nanoparticles. The spraying conditions are: flow rate is 0.3mL / h, voltage 25KV, The receiving distance is 13cm.

[0056] (4) Pectin is mixed with sodium alginate in a mass ratio of 30%, and dissolved in water to obtain a sodium alginate-pectin solution with a mass fraction of 1.5%.

[0057] (5) take American ginseng and Rhodiola rosea extract-chitosan nanoparticles prepared...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an anti-fatigue microcapsule with a slow release effect, a preparation method and application. A dual embedding method is adopted and comprises the following steps: primary embedding: embedding American ginseng and/or rhodiola rosea extract into chitosan, gelatin or zein to prepare nanoparticles; and secondary embedding: embedding the nanoparticles into a sodium alginate-pectin-chitosan composite microcapsule. The secondary embedding further shields the bitterness of the American ginseng and/or the rhodiola rosea extract, and improves the acceptability of consumers forfood added with the American ginseng and the rhodiola rosea extract: and the release of functional components in the digestion process is obviously delayed, and the functional components in the bloodplasma can be continuously kept at a certain concentration, so that the function exertion is facilitated. According to the preparation method, the particle size of the microcapsule can be reduced, theaverage particle size of the finally obtained microcapsule after drying is about 200 microns, and application of the microcapsule in a food system is facilitated.

Description

technical field [0001] The invention specifically relates to an anti-fatigue microcapsule with sustained release effect, a preparation method and application. Background technique [0002] Nowadays, the pace of life is accelerating, and the pressure of work is increasing. More and more people work overtime and stay up late. It is common for people to work during the day and often experience fatigue, lack of energy, and drowsiness. When lack of sleep and energy fatigue, the brain is not fully rested, which can easily cause insufficient oxygen supply to the brain and make people feel drowsy. When this state lasts, it is easy to enter the state of frequent fatigue, which seriously affects the quality of life and work. [0003] The saponins contained in American ginseng can effectively enhance the function of the central nervous system, refresh the mind, relieve stress, and enhance memory; It is suitable for the elderly and infirm, those who often catch colds and the daily hea...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A23L33/105A23L2/39A23P10/30A61K36/41A61K9/50A61P39/00B01J13/02
CPCA23L33/105A23L2/39A23P10/30A61K36/258A61K36/41A61K9/5036A61P39/00B01J13/02A23V2002/00
Inventor 蒋胜王琳王文水吕新刚
Owner 蒋胜
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap