A cooling and rewarming system for vitrification preservation of biological materials
A biological material and vitrification technology, applied in the preservation, application, and animal husbandry of human or animal bodies, can solve the problems of untraceable preservation process, difficult operation, and low preservation efficiency, so as to achieve traceability and reduce Difficulty in operation and the effect of reducing potential safety hazards
Active Publication Date: 2021-09-17
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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Problems solved by technology
[0003] In order to overcome the problems of poor consistency, difficult operation, low storage efficiency, and untraceable storage process in the existing low-temperature storage methods for biological materials, the present invention provides a cooling and rewarming system for vitrification storage of biological materials
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[0030] The present invention will be further described through the embodiments below in conjunction with the accompanying drawings.
[0031] see figure 1 , a cooling and reheating system for vitrification preservation of biological materials, including a reheating and cooling workbench mechanism, a gas source tank 1, a cooling working medium container 2, a rewarming working medium container 3, an external liquid storage tank 4, and an external liquid supply tank 5 and electric air pump 20.
[0032] see figure 2 , the reheating and cooling workbench mechanism includes a fluidic mechanism, a clamping mechanism, a controller and a workbench casing 81 .
[0033] The jet flow mechanism includes a pair of jet flow generating mechanisms, that is, an upper jet flow generating mechanism and a lower jet flow generating mechanism.
[0034] The upper jet generating mechanism includes an upper jet generator 813 , an upper clamping plate 83 and a transition plate 85 . The transition pl...
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The invention relates to a cooling and rewarming system for vitrification preservation of biological materials, belonging to the technical field of biological material preservation. The system consists of a reheating and cooling workbench mechanism, an air source tank, a cooling working medium container, a rewarming working medium container, an external liquid storage tank, an external liquid supply tank, and an electric air pump; the reheating and cooling workbench mechanism includes Injection mechanism, clamping mechanism, controller and workbench casing. When working, open the gas source tank, and the high-pressure gas in the gas source tank passes into the cooling medium container or the reheating working medium container to press the working medium out, and flows into the jet in the reheating and cooling workbench mechanism through the second three-way valve The generator makes the high-speed jet of working medium impact on the sample box, and implements liquid nitrogen jet cooling or warm water jet reheating operation on the sample box symmetrically. The invention reduces the problem of poor consistency caused by manual operation and improves the preservation efficiency.
Description
technical field [0001] The invention belongs to the technical field of preservation of biological materials, and in particular relates to a cooling or rewarming system for low-temperature vitrification preservation of biological materials such as cells, tissues and organs. Background technique [0002] Low temperature preservation is currently the only effective long-term preservation method for many biological materials, and vitrification preservation is one of the important methods, which avoids the traditional slow-speed preservation by transforming liquid substances into a highly viscous amorphous state (glass state). The dehydration process of the cryopreservation method prevents the internal tissues of biological samples from producing (or only produces a small amount of) ice crystals during the preservation process, so that the cells are less damaged by low temperature. The key to achieving vitrification is to quickly cool down and rewarm biological samples. The exist...
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IPC IPC(8): A01N1/02
CPCA01N1/0242A01N1/0252
Inventor 周晓明冷顺刘杰刘浩
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA