Application of thymosin or derivative thereof and medicine for treating pleasant sensation deficiency type depression
A technology of anhedonia and thymosin, applied in the field of pharmacy, can solve the problems of acute poisoning, disordered balance relationship, anhedonia, etc., achieve good curative effect, improve anhedonia-type depression symptoms, and have no toxic and side effects
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[0024] 1. Experimental animals
[0025] Sexually mature female C57BL / 6 mice, body weight (20-22g), were purchased from Shandong Experimental Animal Center (animal quality certificate: No. 37009200018914, license number: SCXK (Lu) 2014000). Breeding environment: 4 mice per cage, 22±1°C temperature, 50±10% humidity, 12h light-dark cycle, free to eat and drink. The feeding and operation of experimental animals complied with the relevant regulations on the feeding and use of experimental animals of Guangdong Ocean University.
[0026] Thymosin β4: purchased from Guangzhou Binshang Biotechnology Co., Ltd.
[0027] Rats and mice maintained powder feed: provided by Guangdong Experimental Animal Center.
[0028] 2. Experimental plan
[0029] After the animals were repurchased and adapted to the laboratory for one week, they were randomly numbered and grouped into 3 groups, as shown in Table 1:
[0030] Table 1. Grouping of experimental animals
[0031]
[0032] The CUMS group an...
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