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Quality control system and method for tumor sample NGS detection process

A detection process and quality control technology, which is applied in the field of quality control system of tumor sample NGS detection process, can solve the problems that quality control methods are difficult to carry out comprehensive quality control and affect the effect of quality control

Active Publication Date: 2020-12-18
浙江绍兴鼎晶生物医药科技股份有限公司
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0006] The present invention can solve the problem that the existing quality control method is difficult to comprehensively carry out quality control and affects the effect of quality control

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  • Quality control system and method for tumor sample NGS detection process
  • Quality control system and method for tumor sample NGS detection process
  • Quality control system and method for tumor sample NGS detection process

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Embodiment Construction

[0084] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments It is some embodiments of the present invention, but not all of them. Based on the implementation manners in the present invention, all other implementation manners obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0085] Accordingly, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the invention. Based on the implementation manners in the present invention, all other im...

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Abstract

The invention discloses a quality control system and method for a tumor sample NGS detection process, and the quality control system comprises an experiment data storage system, a quality control datacalculation system, a quality control data statistics system, and a quality control result display system. The quality control method comprises the steps of acquiring experimental data, obtaining a database, downloading, calculating, extracting features, training a model by quality control, controlling quality and displaying a quality control result. According to the present invention, the comprehensive quality control in the tumor sample NGS detection process is achieved by starting from the experiment source and starting from the quantification result of the cell number of each step, and the quality control of the single step can be split so as to ensure that the experiment of each step is performed under the condition of the qualified quality control, such that the cost consumption ofthe experiment continuing due to the unqualified quality control is reduced, and the experiment efficiency is improved. Meanwhile, the authority and the reliability of a medical detection company canalso be improved.

Description

technical field [0001] The invention belongs to the technical field of tumor detection quality control, and in particular relates to a quality control system for the NGS detection process of tumor samples. Background technique [0002] With the maturity of Next Generation Sequencing (NGS) technology and the continuous reduction of cost, NGS has been promoted to clinical application on a large scale, especially in the clinical practice of tumors, where it is used to sequence tumor driver genes, target More technologies for early screening and recurrence monitoring are under development. [0003] The NGS detection method of tumor samples involves sample collection, transportation, storage and processing before analysis; "wet experiment" (primer or probe design and synthesis, nucleic acid extraction, library preparation, on-machine sequencing) and "dry experiment" in analysis are The whole testing process including bioinformatics analysis process; post-analysis report and inte...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B30/00G16B25/20G06N3/00
CPCG06N3/006G16B25/20G16B30/00
Inventor 史善甫丁首太严志祥沈伟强罗鹏蔡丽君
Owner 浙江绍兴鼎晶生物医药科技股份有限公司