A nucleic acid analysis cartridge and nucleic acid analysis equipment

Abstract

The invention discloses a nucleic acid analysis cartridge and nucleic acid analysis equipment. The nucleic acid analysis cartridge comprises: a cartridge body and a silica gel film transfer part arranged on the cartridge body and capable of moving along a set direction; the cartridge body is provided with a storage A liquid chamber, an auxiliary liquid storage chamber, a detection structure, a sampling channel and an exhaust channel that are all connected to the liquid storage chamber. There are at least two liquid storage chambers and they are distributed in sequence along the set direction. One-to-one correspondence, the auxiliary liquid storage chamber located at the end along the set direction can communicate with the detection structure; the surface of the liquid storage chamber and the surface of the auxiliary liquid storage chamber are both sealed and connected with the silicone membrane transfer part, and the silicone membrane transfer part moves along the set direction The silica gel membrane can be connected to each liquid storage chamber and its corresponding auxiliary liquid storage chamber in turn. The above-mentioned nucleic acid analysis cartridge can use the silica gel membrane method for fully integrated and automated analysis of nucleic acids, which is conducive to promoting the popularization of molecular diagnostic techniques.

Description

technical field [0001] The invention relates to the technical field of in vitro diagnosis, more specifically, to a nucleic acid analysis cartridge and nucleic acid analysis equipment. Background technique [0002] In the field of in vitro diagnosis, molecular diagnosis is a commonly used technology. Specifically, molecular diagnosis is a diagnostic technology that uses nucleic acid or protein as a biomarker for clinical detection, providing information and information for the prediction, diagnosis, prevention, treatment, prognosis and outcome of diseases. Decision basis. [0003] Molecular diagnostic technology involves nucleic acid extraction, and silica gel membrane method is one of the commonly used techniques for nucleic acid extraction. When using the silica gel membrane method for nucleic acid extraction, various reagents such as lysate, cleaning solution, and eluent are required, and multi-step operations of opening the cap and adding liquid, supplemented by high-spe...

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Problems solved by technology

Such a design has high requirements on the laboratory environment, and the operation of personnel is time-consuming. It is difficult to meet the needs of areas with backward medical infrastructure and on-site instant detection.

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