Self-adjusting opening and closing hot cover and full-automatic gene amplification instrument using hot cover

A technology of gene amplification and self-regulation, applied in the field of gene amplification instruments, can solve the problems of troublesome operation, cracking of PCR tubes, inflexible operability, etc., and achieve the effect of constant pressing force

Pending Publication Date: 2021-03-16
HANGZHOU BIOER TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most gene amplification instruments basically use manual opening and heating to adjust the pressure, which is time-consuming and laborious, and the operability is not flexible enough. The results of different operators are different, which affects gene amplification. As a result, there may even be a phenome

Method used

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  • Self-adjusting opening and closing hot cover and full-automatic gene amplification instrument using hot cover
  • Self-adjusting opening and closing hot cover and full-automatic gene amplification instrument using hot cover
  • Self-adjusting opening and closing hot cover and full-automatic gene amplification instrument using hot cover

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Embodiment Construction

[0017] The present invention will be further described below in conjunction with accompanying drawing.

[0018] Such as figure 1 and 2 As shown, a self-adjusting opening and closing thermal lid includes a driving mechanism and a thermal lid module 1; the driving mechanism includes a stepping motor 2, a belt transmission mechanism 3, a rotating shaft, a crank 4, a slider and a connecting rod 5; the belt transmission mechanism 3 is composed of a driving pulley, a conveyor belt and a driven pulley; the driving pulley is fixed to the output shaft of the stepping motor 2, and is connected with the driven pulley fixed on the rotating shaft through a conveyor belt; one end of the two cranks 4 is connected to the rotating shaft The two ends are respectively fixed; the chute provided by the two cranks along the length direction and the two sliders form a sliding pair respectively; the two sliders are respectively hinged with the bottom ends of the two connecting rods 5 . The hot cove...

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PUM

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Abstract

The invention discloses a self-adjusting opening and closing hot cover and a full-automatic gene amplification instrument using the hot cover. An existing gene amplification instrument adopts a manualuncovering mode, and the provided pressure varies from person to person, so that the gene amplification effect is influenced. The hot cover comprises a driving mechanism and a hot cover module, wherein the hot cover module comprises a hollow hinged frame, a supporting block, a guide sleeve, a sliding rod, a movable pressing plate, coil springs, a hot cover shell and an annular rubber pad. According to the invention, in a closing process of the hot cover shell, a crank and a connecting rod are driven through a stepping motor, then the connecting rod drives the movable pressing plate, finally the closing process is achieved through acting force of the springs, and it is guaranteed that constant pressing force is kept in the closing process of the hot cover shell under the action of the springs; and the coil springs wound at the two ends can provide constant acting force for the movable pressing plate, so that it is guaranteed that the pressing force of the movable pressing plate on a PCR tube is constant, PCR tubes of 0.1 ml and 0.2 ml can be adapted at the same time, the operation is automatically completed, and after the pressing force of the movable pressing plate on the PCR tubeis pre-adjusted, PCR tube pressing cracking caused by overpressure can be avoided.

Description

technical field [0001] The invention belongs to the technical field of gene amplification instruments, and in particular relates to a self-regulating opening and closing thermal cover for universal 0.1 and 0.2 ml PCR tubes and a fully automatic gene amplification instrument using the thermal cover. Background technique [0002] The gene amplification instrument is a basic instrument used in the polymerase reaction in the biomedical field. It provides a stable and adjustable temperature environment. As a DNA fragment amplification instrument, it has been widely used in the industry. Most gene amplification instruments basically use manual opening and heating to adjust the pressure, which is time-consuming and laborious, and the operability is not flexible enough. The results of different operators are different, which affects gene amplification. As a result, there may even be a phenomenon that the PCR tube is cracked by excessive pressure; and the universality of PCR tube con...

Claims

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Application Information

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IPC IPC(8): C12M1/38C12M1/36C12M1/34C12M1/02C12M1/00
CPCB01L7/52
Inventor 吴四俚李冬方赛贺贤汉
Owner HANGZHOU BIOER TECH CO LTD
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