Protein immune adsorption device based on alternating mechanism
An immunoadsorption and protein technology, applied in the field of medical devices, can solve the problems of prolonging the patient's medical treatment time, increasing the pain of the patient, and poor safety performance, and achieving the effect of reducing the time of protein immunotherapy, reducing the hidden danger of treatment, and reducing the work intensity.
Pending Publication Date: 2021-04-16
CENT SOUTH UNIV
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Problems solved by technology
The adsorption treatment can only be continued after the adsorption column is eluted and regenerated, which not only greatly prolongs the time for patients to seek medical treatment, but also increases the pain of patients.
And it greatly increases the hidden danger of patients' treatment
In addition, the existing plasma protein separation immunoadsorption device has a low level of automation and intelligence, and its safety performance is poor
As a result, the work efficiency of medical staff is not high, and there are many hidden dangers in treatment
Method used
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[0035] The following is attached Figure 1-12 The present invention is described in further detail with embodiment, but protection scope of the present invention is not limited to this:
[0036] A protein immunoadsorption device based on a rotation mechanism, such as figure 1 , figure 2 and Figure 9 As shown, it mainly includes: 1. Prefilling solution storage bottle 1; 2. Prefilling solution storage bottle 1 containing heparin; 3. Two-input and two-outlet combination valve 1; 4. Arterial port; 5. Connecting tube L1; 6. Blood pump; 7. Arterial jug; 8. Arterial jug pressure sensor; 9. Plasma separator; 10. Connecting tube L3; 11. Connecting tube L2; ;14. Heparin-containing priming solution storage bottle 2; 15. Prefilling solution storage bottle 2; 16. Eluent storage bottle; 17. Equilibrium solution storage bottle; 18. Storage solution storage bottle; 19. Five inputs and one output Combination valve; 20. Connecting pipe L5; 21. Two-in and two-out combined valve 2; 22. Conn...
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The invention discloses a protein immune adsorption device based on an alternating mechanism. The protein immune adsorption device comprises a blood side circulation pipeline, a plasma side circulation pipeline, a cleaning unit, a detection unit and a control unit. The control mode is divided into logic control, signal constraint control and manual intervention control. The working process is divided into a to-be-treated pre-flushing stage, an extracorporeal circulation establishing stage, a protein immunoadsorption treatment and adsorption column elution regeneration stage and a storage stage. According to the invention, protein immunologic continuous treatment can be realized, the time for protein immunologic treatment of a patient is greatly shortened, the defect that the existing device needs an adsorption column to elute and regenerate to continue treatment is overcome, and the treatment hidden danger caused by long-time protein immunologic adsorption treatment of the patient is reduced. The automation degree is high, the control safety is good, and the working intensity of medical staff is greatly reduced.
Description
technical field [0001] The invention relates to the technical field of medical devices, in particular to a protein immunoadsorption device. Background technique [0002] Protein immunoadsorption (immunoadsorption, IA) therapy is a blood purification technology developed in the past 15 years, which is different from general non-specific hemoperfusion. Protein immunoadsorption therapy is a new technology developed on the basis of plasma exchange. Its advantage is that it has better selectivity for the removal of pathogenic factors in plasma, and the loss range and quantity of useful components in plasma are smaller. Various adverse effects brought about by the input. Protein immunoadsorption is to extract the blood from the patient's arterial end, and separate the plasma in the blood from blood cells and platelets through a plasma separator. The plasma enters the adsorption column to absorb the antibodies in it. Mix and infuse into the patient's arterial segment. Thereby re...
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IPC IPC(8): A61M1/36
Inventor 李志勇陈磊鑫肖湘成陈磊蒲佳曦
Owner CENT SOUTH UNIV