Magnetoencephalogram source positioning method and device based on Tucker decomposition and ripple time window

Abstract

The invention provides a magnetoencephalogram source positioning method and device based on Tucker decomposition and a ripple time window. The device comprises a magnetoencephalogram sensor which is used for obtaining a first magnetoencephalogram signal of a user; a ripple detection unit which is used for detecting the ripple time window in the first magnetoencephalogram signal through a root-mean-square method to serve as a time window for source positioning and obtaining the first magnetoencephalogram signal in the ripple time window to serve as a second magnetoencephalogram signal; a high-order orthogonal iteration based Tucker decomposition unit which is used for carrying out Tucker decomposition on the original tensor of the second magnetoencephalogram signal to calculate an estimated value of the original tensor; and a source positioning unit which is used for calculating a covariance matrix for the estimated value and calculating a source position corresponding to the second magnetoencephalogram signal through an LCMV inverse problem solving method in a beamforming method. According to the method, the influence of noise signals is eliminated, the calculation complexity is reduced, the consistency of each calculation result is ensured, and the positioning accuracy of the epileptogenic region is improved.

Description

technical field [0001] The invention relates to a magnetoencephalogram source location method and device based on Tucker decomposition and ripple time window, belonging to the field of biomedicine. Background technique [0002] Clinically, up to one-third of epilepsy patients have intractable epilepsy. However, the drug treatment with antiepileptic drugs is difficult to be effectively controlled. The epileptic focus can affect the excitability of the cortex, resulting in abnormal discharges, not only directly affecting the focus or surrounding tissues, but also affecting distant brain regions. Therefore, these patients require surgical resection of the epileptogenic focus (seizure-induced area) to achieve seizure freedom, and postoperative seizures depend on the localization of the epileptogenic focus (seizure-induced area). However, this area has been difficult to pin down due to the lack of tools to directly measure it. [0003] Magnetoencephalography (MEG) is a non-inv...

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Problems solved by technology

However, this area has been difficult to determine due to the lack of tools to directly measure the area

[0003] Magnetoencephalography (MEG) is a non-invasive, real-time method for monitoring brain function. In the past few decades, several brain source localization methods based on EEG or EEG have been proposed, such as spike-based dipole- fitting method, but the positioning accuracy of these methods still cannot meet the needs of preoperative precise positioning, the calculation complexity is high, and the positioning results are easily affected by noise signals. For the same MEG signal, the results of multiple positioning are biased and poor consistency

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