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Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition

A technology of corticosteroids, pharmaceutical compositions, used in the field of treatment and prevention of asthma symptoms, capable of solving problems such as unreached results

Pending Publication Date: 2021-06-18
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when aimed at simulating 10mg (atorvastatin calcium) was abandoned in 2014 when a phase 3 "real use" trial of OTC use failed to meet its primary goal because patients followed instructions to check their LDL cholesterol (LDL-C) levels and have not achieved satisfactory results in checking their LDL-C levels and taking appropriate action based on their test results

Method used

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  • Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition
  • Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition
  • Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition

Examples

Experimental program
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specific Embodiment approach

[0261] In one aspect, the present disclosure provides methods, software and computer systems for eligibility of a human individual for over-the-counter delivery of a corticosteroid pharmaceutical composition for the treatment or prevention of asthma symptoms. In one embodiment, a computer system (eg, figure 2 The computer system 250 in ) includes instructions for conducting surveys of individuals (for example, including by figure 2 Survey questions 208 and 212 given by evaluation module 252 in ) to obtain filters for at least two series (e.g., respectively figure 2 Information about individuals necessary for the filters 216 and 222 in the first filter category 214-1 and the second filter category 220-2) to function. The computer system also includes instructions for running the findings against the filter. Filter 216 in first series of filters 214 prevents authorization to provide OTC corticosteroids when the individual's findings identify a contraindication for OTC corti...

example 1

[0332]Example 1: A computer system configured to identify an individual for a budesonide pharmaceutical composition (e.g., 16,17-(butylenebis(oxy))-11, for use in the treatment or prevention of asthma symptoms 21-dihydroxy-, (11-β,16-α)-pregna-1,4-diene-3,20-dione) is eligible for over-the-counter delivery. The computer system includes instructions for conducting a survey of an individual. The survey is used to obtain one or more results indicating whether the individual is allergic to dairy products, whether the individual is already using steroid medication, the age of the individual, the lung function status of the individual, the severity of asthma in the individual, whether the individual has liver problems, the individual Whether the individual has an untreated infection, the individual's surgical status, the individual's bone density status, whether the individual has ever had cataracts or glaucoma, and whether the individual is using budesonide that interacts (e.g., ph...

example 2

[0342] Example 2: A computer system configured to identify an individual for use in the treatment or prevention of a ciclesonide pharmaceutical composition (2-methylpropionic acid 2-[(1S,2S,4R,8S ,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxyl-9,13-dimethyl-16-oxo-5,7-dioxolane[10.8.0.0 2,9 .0 4,8 .0 13,18 ]eicos-14,17-dien-8-yl]-2-oxoethyl ester) is eligible for over-the-counter delivery. The computer system includes instructions for conducting a survey of an individual. The survey is used to obtain one or more results indicating whether the individual is already using steroid medication, the age of the individual, the lung function status of the individual, the severity of asthma in the individual, whether the individual has an untreated infection, the surgical status of the individual , the individual's bone density status, and whether the individual has ever had cataracts or glaucoma.

[0343] The computer system runs the findings against a first set of filters, each associa...

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PUM

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Abstract

A method is provided for treating or preventing symptoms of asthma in a subject in need thereof by administering a corticosteroid pharmaceutical composition to a subject qualified for over-the-counter access to the corticosteroid pharmaceutical composition. In some embodiments, the corticosteroid pharmaceutical composition includes a class B corticosteroid, a glucocorticosteroid, budesonide, ciclesonide, fluticasone furoate, mometasone furoate, fluticasone propionate, or beclomethasone dipropionate.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application Serial No. 62 / 685,213, filed June 14, 2018, which is hereby incorporated by reference in its entirety. technical field [0003] The present disclosure relates generally to methods for treating and preventing asthma symptoms by administering an over-the-counter corticosteroid pharmaceutical composition to an individual in need thereof, wherein the individual is eligible to obtain the composition over-the-counter . Background technique [0004] Although asthma is one of the most common diseases worldwide, its symptoms are also the most preventable with proper care. CDC Vital Signs (2011), Asthma in the US, Center for Disease Control and Prevention. As of 2016, according to the CDC, 1 in 13 adults in the United States has asthma. Centers for Disease Control, Uncontrolled Asthma among Persons with Asthma, print edition (2016). Of the approximately ...

Claims

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Application Information

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IPC IPC(8): G16H10/20A61K31/573G16H20/10G16H50/20
CPCG16H10/20G16H20/10G16H50/20A61K31/58A61K31/573A61P11/06G16H70/40G06F16/9038G06F16/9035G06Q30/0637
Inventor R·P·普莱伯尔斯基J·菲罗尔
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