Pharmaceutical composition containing beta2 agonists and steroids, and uses thereof

A technology of β2 receptors and compositions, applied in the direction of drug combination, drug delivery, medical preparations containing active ingredients, etc.
CN101433541AInactive Publication Date: 2009-05-20SHENYANG PHARMA UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2009-05-20
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the medicine technical field, and relates to a pharmaceutical composition of a beta2 receptor agonist and steroid and application thereof, in particular to a pharmaceutical composition of tranditerol or salt thereof, or mabuterol or salt thereof, and fluticasone propionate and application thereof, wherein the mixture ratio of the tranditerol or the salt thereof to the mabuterol or the salt thereof to the fluticasone propionate is 10 to 1-1 to 10,000; and the composition can be a composition which can be atomized in respirable mode, and can be used for preparing an aerosol inhalant and an aerosol. The composition can be prepared into capsules and other formulations with other auxiliary materials after the composition is prepared into dried powder with pharmaceutically acceptable carriers. The composition can significantly improve pulmonary function, and can control obstructive or phlogistic airway diseases or slow down depravation of the diseases. The composition can be used for preparing medicaments for salving and treating the obstructive or phlogistic airway diseases.
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Description

technical field

[0001] The invention belongs to the technical field of medicine and relates to beta 2 The pharmaceutical composition of receptor agonist and steroid and application thereof, specifically relates to the pharmaceutical composition of trabutanterol or its salt or mabuterol or its salt and fluticasone propionate and its application in the treatment of inflammatory or obstructive pneumothorax use in road diseases. Background technique

[0002] Trabutinaterol, especially in the form of its hydrochloride salt, is a bronchodilator used in the treatment of inflammatory or obstructive airway diseases. Mabuterol, especially in the form of its hydrochloride salt, is a bronchodilator for the treatment of asthma. It has a stronger relaxing effect on airway smooth muscle, an increase in airway resistance induced by histamine, and an inhibitory effect on experimental asthma than albuterol , The duration is also long, and no tolerance is seen. Fluticasone propionate, 6α,9α...

Claims

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