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Breathabolism system

A measurement system and air technology, applied in the field of biological experiments, can solve the problems of lack of real-time combination of inhalation exposure and expiratory imprint, and achieve the effect of convenient experimental operation

Active Publication Date: 2022-03-18
RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] In the traditional exhalation metabolome and other metabolome studies, the time point metabolism after inhalation exposure has been detected, but there is still a lack of real-time combination of inhalation exposure and exhalation imprinting technology

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Embodiment Construction

[0077] The disclosure provides a breath metabolism measurement system, including: an organic vapor micro-injection module, an air pump, a monomer breath imprint sampling module, an aerosol nozzle, a gas solenoid valve, a zero-stage air purifier, and an automatic solvent desorption module; The first end of the air pump is connected to the outlet of the organic vapor micro-injection module, the second end of the air pump is connected to the first end of the liner; the gas outlet of the monomer breath imprint sampling module is connected to the second end of the liner, and the liner Stirrer adsorption and extraction rods sample the exhaled metabolites of the experimental animals; the air outlet of the individual breath imprint sampling module is connected to the nozzle interface of the aerosol nozzle, and its air inlet is connected to the air outlet of the zero-stage air purifier Connection; the gas solenoid valve controls the zero-level air to enter the monomer breath imprint sam...

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Abstract

The disclosure provides a breath metabolism measurement system, including: an organic vapor micro-injection module, an air pump, a monomer breath imprint sampling module, an aerosol nozzle, a gas solenoid valve, a zero-stage air purifier, and an automatic solvent desorption module; The first end of the air pump is connected to the outlet of the organic vapor micro-injection module, the second end of the air pump is connected to the first end of the liner; the gas outlet of the monomer breath imprint sampling module is connected to the second end of the liner, and the liner Stirrer adsorption and extraction rods sample the breath imprints of the experimental animals; the air outlet of the monomer breath imprint sampling module is connected to the nozzle interface of the aerosol nozzle, and its air inlet is connected to the air outlet of the zero-stage air purifier ;The gas solenoid valve controls the zero-level air to enter the monomer breath imprint sampling module and simultaneously blocks inhaled exposure substances from entering the monomer breath imprint sampling module; the automatic solvent desorption module is used to absorb the breath metabolites collected by the stirring bar adsorption extraction rod to test.

Description

technical field [0001] The present disclosure relates to the field of biological experiments, in particular to a breath metabolism measurement system. Background technique [0002] In the traditional exhalation metabolome and other metabolome studies, the time point metabolism after inhalation exposure has been detected, but there is still a lack of real-time combination of inhalation exposure and exhalation imprinting technology. [0003] In the fields of biology, medicine, and pharmacy, the real-time response of exhaled metabolome changes to inhalation exposure plays an irreplaceable role in revealing the immediate health effects of exogenous substances entering the organism through the inhalation route. [0004] Therefore, it is urgent to provide a breath metabolic measurement system that can combine natural inhalation exposure and breath imprinting technology in real time. Contents of the invention [0005] (1) Technical problems to be solved [0006] The present dis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/497G01N1/34A61B10/00
CPCG01N33/497G01N1/34A61B10/00A61B2010/0087
Inventor 胡立刚陶晨江桂斌
Owner RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI