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Blood glucose testing method and device based on OCTA

A testing method, blood sugar technology, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve problems such as changing vascular osmotic pressure, affecting red blood cell morphology, etc., and achieve the effect of improving accuracy

Active Publication Date: 2021-06-29
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the area of ​​blood flow, the rise in blood glucose concentration not only affects the above-mentioned refractive index mismatch phenomenon, but also changes the osmotic pressure in blood vessels, which in turn affects the morphology of red blood cells

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  • Blood glucose testing method and device based on OCTA
  • Blood glucose testing method and device based on OCTA
  • Blood glucose testing method and device based on OCTA

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Embodiment Construction

[0056] Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, which form a part of this document. It should be noted that these descriptions and examples are illustrative only, and should not be construed as limiting the scope of the present invention. The protection scope of the present invention is defined by the appended claims, and any changes based on the claims of the present invention All are protection scope of the present invention.

[0057] In order to facilitate the understanding of the embodiments of the present invention, each operation is described as a plurality of discrete operations, however, the order of description does not represent the order in which the operations are performed.

[0058] Embodiments of the present invention are as follows:

[0059] For the three-dimensional space of sample measurement, this description adopts x-y-z three-dimensional space coordinate representation. ...

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Abstract

The invention discloses a blood glucose testing method and device based on OCTA. The method comprises the following steps: performing OCT scanning imaging on a target tissue area at N different time points to obtain an OCT signal of the target tissue area; calculating a scattering coefficient according to depth direction OCT signal features; generating an OCTA blood flow contrast matrix according to time dimension OCT signal features; distinguishing scattering coefficients of the blood flow area and the non-blood flow area through an OCTA blood vessel mask; and obtaining a blood glucose monitoring curve according to the linear fitting relationship between the scattering coefficient of the blood flow area and the non-blood flow area and the blood glucose concentration for monitoring the blood glucose concentration. While realizing non-invasive blood glucose monitoring based on OCT, the method and device can use OCTA to guide selection of the target area in the tested tissue, and effectively improve accuracy of OCT non-invasive blood glucose detection technology.

Description

technical field [0001] The invention relates to a blood sugar testing method and device in the field of non-invasive monitoring of blood sugar concentration, in particular to an OCTA-based blood sugar testing method and device. [0002] technical background [0003] Diabetes is a metabolic disease characterized by abnormal blood sugar levels. With the improvement of people's living standards, the incidence of diabetes continues to increase. It is estimated that by 2045, there will be about 700 million diabetics worldwide. However, the current treatment methods for diabetes are very limited, and patients need long-term oral medication or insulin injection to intervene in blood sugar, so as to control the progression of the disease. For diabetic patients, self-blood glucose needs to be monitored frequently based on fingertip blood sampling throughout the day. This invasive blood glucose testing method greatly affects the quality of life of diabetic patients. [0004] In rece...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455A61B5/00
CPCA61B5/1455A61B5/14532A61B5/7203A61B2560/0233
Inventor 李鹏刘开元
Owner ZHEJIANG UNIV