Method and kit for simultaneously detecting vancomycin and norvancomycin in blood sample and application thereof
A technology for norvancomycin and blood samples, which is applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of unstable signals, poor detection sensitivity, and low detection signals, and achieve rapid operation analysis, low cost, The effect of accurate test results
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment
[0060] (1) Prepare the sample to be tested
[0061] Add the serum to the mixed solution of methanol and acetonitrile containing 0.05% zinc sulfate (methanol / acetonitrile volume ratio is 3 / 2, containing internal standard), shake and centrifuge, take out the supernatant after centrifugation, blow dry with nitrogen and flow The phase was redissolved to obtain the sample to be tested.
[0062] This embodiment compares zinc sulfate, formic acid, hydrochloric acid three kinds of additives, the concentration is respectively 0.05% zinc sulfate, 2% formic acid, 2% acetic acid, it is proved by the test that all can reduce the protein binding of vancomycin and norvancomycin The efficiency has obvious effect, and the concentration of each additive is optimized before the comparison experiment, and the best concentration of each is selected to participate in the comparison. The effect is shown in Table 1 below. Whether or not nitrogen blowing is obtained in the supernatant to be tested af...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com