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Cold compress type medical hydrogel and preparation method thereof

A hydrogel and medical technology, applied in the field of cold compress medical hydrogel and its preparation, can solve problems such as accelerating wound healing, and achieve the effects of relieving pain and increasing gel content

Inactive Publication Date: 2021-07-02
卫纳塞德(北京)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, it was believed that the wound needs to breathe, and maintaining the air permeability of the wound is an important factor for an ideal dressing, but new research proves that an oxygen-free atmospheric environment can promote the proliferation of blood vessels, thereby accelerating wound healing

Method used

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  • Cold compress type medical hydrogel and preparation method thereof
  • Cold compress type medical hydrogel and preparation method thereof
  • Cold compress type medical hydrogel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The cold compress medical hydrogel described in this embodiment includes the following raw material components based on the total amount of the hydrogel:

[0031]

[0032] The preparation method of the cold compress type medical hydrogel described in the present embodiment comprises the following steps:

[0033] (1) Get the selected amount of the water-soluble polymer and fully dissolve it in part of deionized water to make a water-soluble polymer solution for subsequent use;

[0034] (2) Dispersing the selected amount of the succinylated modified starch in deionized water to obtain a succinylated modified starch dispersion for subsequent use;

[0035] (3) Mix the obtained water-soluble polymer solution with the succinylated modified starch dispersion, adjust the pH of the system to 9, and keep the temperature at 40° C. for 1 hour;

[0036] (4) Add a selected amount of the cross-linking agent to the mixture liquid obtained in step (3) and mix evenly, pour it into a ...

Embodiment 2

[0038] The cold compress medical hydrogel described in this embodiment includes the following raw material components based on the total amount of the hydrogel:

[0039]

[0040]

[0041] The preparation method of the cold compress medical hydrogel described in this embodiment is the same as that in Embodiment 1.

Embodiment 3

[0043] The cold compress medical hydrogel described in this embodiment includes the following raw material components based on the total amount of the hydrogel:

[0044]

[0045] The preparation method of the cold compress medical hydrogel described in this embodiment is the same as that in Embodiment 1.

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Abstract

The invention belongs to the technical field of medical biological materials, and particularly relates to a cold compress type medical hydrogel and a preparation method thereof. According to the cold compress type medical hydrogel, a water-soluble polymer, succinylation modified starch, collagen, a cross-linking agent and deionized water are used as a raw material system, and the starch is subjected to succinylation modification, so that the gel performance, the water absorption performance and the strength performance of the starch are further improved, the gel content, the mechanical properties such as the gel strength and the like, and the water absorption performance of the whole hydrogel system are effectively improved, the cooling effect of the hydrogel can be realized, and the hydrogel has the effect of relieving pain by further utilizing the advantage of cooling.

Description

technical field [0001] The invention belongs to the technical field of medical biomaterials, and in particular relates to a cold compress type medical hydrogel and a preparation method thereof. Background technique [0002] The rise of hydrogel dressings benefited from a major conceptual breakthrough in wound healing in the 1980s. Previous treatments believed that wounds need to breathe, and maintaining the air permeability of wounds is an important factor for ideal dressings, but new research proves that an oxygen-free atmospheric environment can promote the proliferation of blood vessels, thereby accelerating wound healing. Hydrogel dressings have been widely valued due to their advantages of automatically adjusting the moisture of the wound, absorbing a small amount of exudate, not sticking to the wound, and being easy to remove. [0003] A conventional hydrogel is a polymer material with a three-dimensional cross-linked network structure, and water is used as a liquid d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00A61F7/02C08J3/075C08J3/24C08L39/06C08L3/06C08L89/00C08L29/04
CPCA61L26/008A61L26/0052A61L26/0061A61F7/02C08J3/075C08J3/246A61F2007/0219C08J2339/06C08J2403/06C08J2489/00C08J2303/06C08J2429/04C08J2389/00
Inventor 王威田霞张俊杰张怡婷李伟王桂保
Owner 卫纳塞德(北京)医疗科技有限公司
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