Resting-state electroencephalogram rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method

A closed-loop feedback, resting state technology, applied in the direction of diagnosis, diagnostic recording/measurement, medical science, etc., can solve problems such as lack, arbitrary and blind stimulation targets, and affect treatment efficiency

Pending Publication Date: 2021-07-30
SHENZHEN PEOPLES HOSPITAL
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AI Technical Summary

Problems solved by technology

However, there are several problems in the clinical practice of rTMS intervention insomnia: first, the choice of stimulation target and stimulation mode is too random and blind, and the treatment effect is random; second, there are significant individual differences in rTMS intervention in patients with chronic insomnia, resulting Uncertainty and unpredictability of treatment effects; 3. At present, in the process of rTMS intervention in insomnia, there is still a lack of an efficient feedback closed-loop diagnosis and treatment system integrating comprehensive evaluation-efficacy prediction-precision intervention, which affects the overall quality of life to a certain extent. Treatment efficiency

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  • Resting-state electroencephalogram rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method
  • Resting-state electroencephalogram rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method

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Embodiment Construction

[0045] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0046] see figure 1 , the present invention provides resting-state EEG rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method, comprising the following steps:

[0047] Step 1: Use the online detection psychobehavioral test system to evaluate and detect the patient's psychological behavior, and then use the EEG signal acquisition device to obtain the resting-state EEG rsEEG signal of the insomnia patient before rTMS treatment.

[0048] Step 1.1: Ask the patient to take a comfortable seat, and use the BrainCap electrode cap and the 64-channel Brainamp DC amplifier for continuous EEG signal recording.

[0049] Step 1.2: The FCz electrode on the top of the head is used as a reference, the AFz electrode on the forehead is used as a ground, the channel impedance is kept below 5 kΩ, and the sampling rate ...

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Abstract

The invention relates to a resting-state electroencephalogram rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method, multi-source heterogeneous data such as EEG, brain structure and psychological behavior detection data are fused, a curative effect prediction model is introduced, and through EEG collection which is low in price and good in portability, curative effect prediction and classification are conducted on insomnia patients; besides, the treatment effect is evaluated and fed back before treatment and during treatment, so that an operator can conveniently adjust a treatment scheme, and dynamic optimization of the prediction model is also facilitated; meanwhile, individualized scheme making and accurate regulation and control under navigation are carried out on patients insensitive to treatment, and reasonable medical suggestions are made for patients with poor effects after 20 times of accurate treatment; the invention relates to a closed-loop feedback diagnosis and treatment system covering evaluation, classification, treatment, reevaluation and retreatment, which greatly saves social resources and medical cost while reducing the blindness of rTMS treatment, improving the accuracy of rTMS treatment and realizing high efficiency of rTMS intervention, and has important application value.

Description

technical field [0001] The invention relates to the technical field of resting-state electroencephalography rTMS diagnosis and treatment, in particular to a resting-state electroencephalography rTMS curative effect prediction and intervention closed-loop feedback diagnosis and treatment method. Background technique [0002] Transcranial magnetic stimulation technology is based on the principle of electromagnetic induction and electromagnetic conversion. It uses the high-voltage capacitor in the stimulation generator to generate high-voltage current to act on the stimulation coil. The time-varying magnetic field generated in the coil penetrates the skull without attenuation and stimulates the cerebral cortex and peripheral areas. Nerve, a magnetic stimulation technology that changes the action potential of nerve cells, affects the metabolism of transmitters in the brain and the electrical activity of nerves, thereby triggering a series of physiological and biochemical reaction...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/369A61B5/375A61B5/256A61B5/291A61B5/16A61N2/02
CPCA61B5/165A61B5/4836A61N2/02
Inventor 郭毅党鸽石雪苏晓琳
Owner SHENZHEN PEOPLES HOSPITAL
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