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Magnetic spiny micro-nano robot capable of directionally delivering medicine, and preparation method thereof

A robot and thorn-like technology, applied in the field of robotics, can solve the problems of inconvenient motion control of micro-nano robots

Pending Publication Date: 2021-07-30
HARBIN MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, the motion control of traditional micro-nano robots in blood vessels is relatively inconvenient. How to design micro-nano robots that are easy to control the motion state to complete complex tasks is particularly important.

Method used

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  • Magnetic spiny micro-nano robot capable of directionally delivering medicine, and preparation method thereof

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Embodiment Construction

[0023] A magnetic spiny micro-nano robot for directional drug delivery, including pollen particles, which are prepared based on sunflower pollen. There are two main reasons for using sunflower pollen. One is that the preparation process of sunflower pollen is already very advanced. Mature, finished sunflower pollen is easy to obtain; second, the spiny shape of sunflower pollen is obvious, and its structural stability is high, so the micro-nano robot spiny directly obtained after applying magnetic coating to the surface of the substrate using sunflower pollen The shape is fine and uniform. exist figure 1 In the middle, from left to right are sunflower pollen particles with spiny structure, and then through layer / surface sol-gel to obtain sunflower pollen particles with spiny magnetic coating, and then high-temperature carbonization to obtain degradable The independent magnetic spiny micro-nano robot, the magnetic spiny micro-nano robot is loaded with drugs, and finally the lub...

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Abstract

The invention relates to a robot, and concretely relates to a magnetic micro-nano robot capable of directionally delivering a medicine, and a preparation method thereof. The magnetic micro-nano robot capable of directionally delivering the medicine comprises pollen particles, and magnetic coatings are attached to the surfaces of the pollen particles. The preparation method of the magnetic micro-nano robot capable of directionally delivering the medicine comprises the following steps: 1, extracting pollen, and grinding the pollen to obtain pollen particles; 2, cleaning the pollen particles twice to obtain clean pollen particles; 3, drying the clean pollen to obtain dried pollen particles; 4, applying a magnetic coating containing Fe-O to the dried pollen particles through a surface sol-gel method to obtain coated particles; 5, processing the coated particles through high-temperature carbonization to obtain a magnetic spiny micro-nano robot; and 6, wrapping the surface of the magnetic spiny micro-nano robot with a medicine layer, and soaking the magnetic spiny micro-nano robot in simethicone for 24 h to form a lubricating layer.

Description

technical field [0001] The invention relates to a robot, more specifically a magnetic spiny micro-nano robot for directional medicine delivery and a preparation method thereof. Background technique [0002] Micro-nano robots have the characteristics of small size, light weight, and large thrust-to-weight ratio. Especially in the field of biomedicine, micro-nano robots can efficiently load therapeutic drugs and targeting factors, and serve as delivery carriers for targeted drugs in specific tissues and organs. Targeted at the target, so as to achieve precise targeted treatment of the tumor lesion area. [0003] However, the motion control of traditional micro-nano robots in blood vessels is relatively inconvenient. How to design micro-nano robots that are easy to control the motion state to complete complex tasks is particularly important. Contents of the invention [0004] The purpose of the present invention is to provide a magnetic spiny micro-nano robot for directional...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M31/00
CPCA61M31/00
Inventor 孙备李轶龙王鑫龙李加廷于世民李天龙
Owner HARBIN MEDICAL UNIVERSITY
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