Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method of composition

A composition and rheumatoid technology, applied in the direction of drug combination, drug delivery, pharmaceutical formulation, etc., can solve the problems of treatment failure, inability to inhibit the progress of the disease, and poor treatment effect, so as to reduce adverse reactions and enhance the original drug effect , the effect of avoiding liver and kidney damage

Active Publication Date: 2021-08-06
FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the western medicines currently used in clinical prevention and treatment of RA, such as non-steroidal anti-inflammatory drugs and glucocorticoids, are effective in controlling symptoms, they cannot inhibit the progression of the disease and the destruction of joint structures, and at the same time cover up the clinical manifestations of the progression of the disease; even Combined use of antirheumatic drugs to improve the condition, there are still a considerable proportion of patients who cannot achieve the expected therapeutic goals
In recent years, biological therapy and stem cell transplantation have opened up new ways for the treatment of RA. However, due to limitations such as high price, inability to take orally, and inability to selectively reach target tissues, these methods are only suitable for a small number of specific patients.
At the same time, long-term treatment with western medicine can cause various adverse reactions such as digestive ulcer, bone marrow suppression, skin rash, liver and kidney damage, and leukopenia, and even cause drug-induced diseases, resulting in poor treatment effect or treatment failure.

Method used

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  • Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method of composition
  • Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method of composition

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Effect test

Embodiment 1

[0035] The external ointment used in the present embodiment for the treatment of rheumatoid arthritis is composed of the following traditional Chinese medicines in parts by weight: 12 parts of scorpion, 10 parts of centipede, 15 parts of rhubarb, 25 parts of Phellodendron cortex, 15 parts of frankincense, and 15 parts of myrrh , borneol 5 parts, vaseline 30 parts.

[0036] The preparation method of the traditional Chinese medicine ointment for treating rheumatoid arthritis of the present invention, the specific steps are as follows.

[0037] Step 1. Add 2000ml of water to decoct the traditional Chinese medicine (scorpion, centipede, rhubarb, Phellodendron phellodendri) at 180°C for 1 hour, discard the residue, extract 200-250ml of the supernatant, and set aside.

[0038] Step 2. Heat the extracted supernatant to 120° C., keep the temperature constant, add frankincense and myrrh and decoct for 10 minutes, stirring continuously during the decoction to form solution 1.

[0039] ...

Embodiment 2

[0076] The external ointment used in the present embodiment for the treatment of damp-heat type rheumatoid arthritis is composed of the following traditional Chinese medicines in parts by weight: 15 parts of scorpion, 12 parts of centipede, 18 parts of rhubarb, 20 parts of Phellodendron cortex, 15 parts of frankincense, myrrh 15 parts, 5 parts borneol, 35 parts Vaseline.

Embodiment 3

[0078] The traditional Chinese medicine powder used in this embodiment for sticking treatment of rheumatoid arthritis is composed of the following traditional Chinese medicines in parts by weight: 12 parts of scorpion, 12 parts of centipede, 15 parts of rhubarb, 20 parts of Cortex Phellodendri, 10 parts of Rhizoma Coptidis, and 15 parts of Atractylodes atractylodes 15 parts of frankincense, 15 parts of myrrh, 5 parts of borneol, and 10 parts of high alcohol.

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating damp-heat type rheumatoid arthritis and a preparation method of the composition. The composition comprises the following traditional Chinese medicines in parts by weight: 12-15 parts of scorpion, 10-12 parts of centipede, 15-20 parts of rheum officinale, 20-25 parts of golden cypress, 15-18 parts of frankincense, 12-15 parts of myrrh, 5-8 parts of borneol and 30-50 parts of vaseline. According to the external ointment for treating the damp-heat type rheumatoid arthritis provided by the invention, the traditional Chinese medicine raw materials are combined according to a certain proportion according to the traditional Chinese medicine theory, the compatibility principle of traditional Chinese medicine is met, the original medicine effect of all the components can be enhanced, all the components supplement one another, the external ointment has the effects of clearing heat and eliminating dampness, promoting blood circulation to remove meridian obstruction and relieving swelling and pain, and the pain of patients can be obviously relieved. The traditional Chinese medicine composition of the invention is used for local treatment of damp-heat type rheumatoid arthritis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic, symmetrical polyarthritis. The disease mainly invades the joints of the limbs. In the acute attack, it mostly manifests as local redness, swelling, heat, and pain in the joints. In severe cases, the flexion and extension are unfavorable, affecting the function of the joints. It is a chronic chronic disease. The main pathological changes of RA are chronic inflammation of joint synovium, inflammatory cell infiltration, synovial angiogenesis and pannus formation, erosion of cartilage and bone tissue, resulting in bone destruction. [0003] Although the western medicines currently used in clinical prevention and treatment of RA, such as non-steroi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61K9/14A61P19/02A61P29/00A61P37/02A61K31/045A61K35/646A61K35/648
CPCA61K35/646A61K35/648A61K36/708A61K36/756A61K36/324A61K36/328A61K31/045A61K36/718A61K36/284A61K9/0014A61K9/145A61K9/08A61P19/02A61P29/00A61P37/02A61K2236/331A61K2300/00
Inventor 姜兆荣莫成荣董巡徐丹贺阳刘海云李颖贾晶晶王春波王琳王晶王丹蒋学斯曹明卓
Owner FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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