Skin wound inorganic functional dressing capable of stopping bleeding and promoting healing and preparation method of skin wound inorganic functional dressing

A skin wound and functional technology, applied in the field of biomedicine, can solve problems such as poor hemostasis effect, achieve excellent hemostasis, reduce scar generation, and improve repair efficiency

Inactive Publication Date: 2021-08-10
海南鸿翼医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The patent "Hemostatic and antibacterial biological dressing and its preparation method", application number: 201010293417.3, discloses that nano-silver and hemostatic drugs are uniformly distributed in the biological dressing matrix, but the hemostatic effect is not good

Method used

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  • Skin wound inorganic functional dressing capable of stopping bleeding and promoting healing and preparation method of skin wound inorganic functional dressing
  • Skin wound inorganic functional dressing capable of stopping bleeding and promoting healing and preparation method of skin wound inorganic functional dressing

Examples

Experimental program
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Effect test

Embodiment 1

[0032] An inorganic functional dressing for skin wounds that stops bleeding and promotes healing: it includes the following raw materials in parts by weight: 10 parts of modified bioactive glass, 12 parts of tetrafluoroethane, 3 parts of chitosan, 2 parts of sodium alginate, polyethylene oxide 3 parts of dilute, 8 parts of rice bran extract, 2 parts of laurocaprazine, 1 part of menthol, 4 parts of konjac gum; the molecular weight of chitosan is 200kDa, and the molecular weight of sodium alginate is 50kDa;

[0033] The preparation method of the modified bioactive glass:

[0034] (1) Bioactive glass is prepared by mixing silicon dioxide, sodium oxide, calcium oxide, and phosphorus pentoxide in a molar ratio of 15:1:28:1;

[0035] (2) Modification system preparation: NdBFe nanoparticles are dissolved in a nitrate solution with a volume concentration of 20%. The mass volume ratio g / mL of NdBFe nanoparticles and nitrate solution is 1:15. sexual system;

[0036] (3) Modification m...

Embodiment 2

[0039] An inorganic functional dressing for skin wounds that stops bleeding and promotes healing: it includes the following raw materials in parts by weight: 25 parts of modified bioactive glass, 32 parts of tetrafluoroethane, 10 parts of chitosan, 6 parts of sodium alginate, polyethylene oxide 7 parts of dilute, 20 parts of rice bran extract, 4 parts of lauroazepam, 3 parts of menthol, 10 parts of konjac gum; the molecular weight of chitosan is 6000kDa, and the molecular weight of sodium alginate is 2000kDa;

[0040] The preparation method of the modified bioactive glass:

[0041] (1) Bioactive glass is prepared by mixing silicon dioxide, sodium oxide, calcium oxide, and phosphorus pentoxide in a molar ratio of 27:3:32:1;

[0042] (2) Modification system preparation: NdBFe nanoparticles are dissolved in a nitrate solution with a volume concentration of 30%. The mass volume ratio g / mL of NdBFe nanoparticles and nitrate solution is 3:15. sexual system;

[0043] (3) Modificati...

Embodiment 3

[0046]An inorganic functional dressing for skin wounds that stops bleeding and promotes healing: it includes the following raw materials in parts by weight: 17 parts of modified bioactive glass, 18 parts of tetrafluoroethane, 8 parts of chitosan, 4 parts of sodium alginate, polyethylene oxide 5 parts of dilute, 12 parts of rice bran extract, 3 parts of laurocapram, 2 parts of menthol, 7 parts of konjac gum; the molecular weight of chitosan is 3000kDa, and the molecular weight of sodium alginate is 1000kDa;

[0047] The preparation method of the modified bioactive glass:

[0048] (1) Bioactive glass is prepared by mixing silicon dioxide, sodium oxide, calcium oxide, and phosphorus pentoxide in a molar ratio of 20:2:30:1;

[0049] (2) Modification system preparation: NdBFe nanoparticles are dissolved in a nitrate solution with a volume concentration of 25%. The mass volume ratio g / mL of NdBFe nanoparticles and nitrate solution is 2:15. sexual system;

[0050] (3) Modification ...

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Abstract

The invention provides a skin wound inorganic functional dressing capable of stopping bleeding and promoting healing and a preparation method of the skin wound inorganic functional dressing. The skin wound inorganic functional dressing is prepared from, by weight, 10-25 parts of modified bioactive glass, 12-32 parts of tetrafluoroethane, 3-10 parts of chitosan, 2-6 parts of sodium alginate, 3-7 parts of polyoxyethylene, 8-20 parts of rice bran extracting solution, 2-4 parts of laurocapram, 1-3 parts of menthol and 4-10 parts of konjac glucomannan. According to the dressing, raw materials are reasonably screened, modified bioactive glass and small molecular chitosan are added as antibacterial agents, water-soluble high-molecular polymers such as sodium alginate, polyethylene oxide and a rice bran extracting solution are added, laurocapram, menthol and natural gel konjac glucomannan are combined, and all the raw materials are scientifically proportioned and synergistically play a role; the prepared skin wound inorganic functional dressing has excellent effects of stopping bleeding, neutralizing exudation, inducing epithelial regeneration to promote healing and reducing scars, and has good biocompatibility.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a hemostatic and healing-promoting inorganic functional dressing for skin wounds and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body, and it is a natural barrier to maintain the stability of the internal environment and prevent the invasion of microorganisms; however, the large area exposed to the outside world makes the skin vulnerable to external injuries such as burns and mechanical injuries, which will cause many local and even systemic diseases. Sexual problems, such as increased metabolism, excessive loss of water and protein, immune system disorders, etc., can even be life-threatening if serious. If the wound is covered with an appropriate dressing, it can effectively reduce the severity of hypermetabolism in the patient's body, relieve pain, prevent bacterial infection, and accelerate wound healing. [0003] At presen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/18A61L15/20A61L15/28A61L15/26A61L15/40A61L15/44A61L15/46
CPCA61L15/18A61L15/20A61L15/28A61L15/26A61L15/40A61L15/44A61L15/46A61L2400/04A61L2300/412A61L2300/404A61L2300/236A61L2300/112
Inventor 陈震王虹韵
Owner 海南鸿翼医疗器械有限公司
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