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Micro-fluidic immunoassay combined detection device and use method thereof

An immunoassay and microfluidic technology, applied in chemical instruments and methods, material inspection products, laboratory containers, etc., can solve the problems of large variation, low sensitivity of detection results, and affecting the scope of application, so as to reduce the cost of detection , Improve detection sensitivity and speed, and expand the effect of using scenarios

Pending Publication Date: 2021-08-20
XIAMEN XIANMING BIOTECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] However, due to uncontrollable factors such as ineffective washing and other uncontrollable factors in the detection process based on lateral flow chromatography, the detection results have low sensitivity and large variation, and clinical applications are prone to missed diagnosis and misdiagnosis, which affect its application range

Method used

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  • Micro-fluidic immunoassay combined detection device and use method thereof
  • Micro-fluidic immunoassay combined detection device and use method thereof
  • Micro-fluidic immunoassay combined detection device and use method thereof

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Embodiment Construction

[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments It is some embodiments of the present invention, but not all of them. Based on the implementation manners in the present invention, all other implementation manners obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention. Accordingly, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the invention. Based on the implementation manners in the present invention, all other implement...

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Abstract

The invention provides a micro-fluidic immunoassay combined detection device. The micro-fluidic immunoassay combined detection device comprises a base, a micro-fluidic reactor, a washing assembly and an upper cover, the base is provided with a groove; the micro-fluidic reactor is arranged in the groove; the washing assembly is arranged in the groove; the upper cover is covered on the base; the micro-fluidic reactor comprises a plurality of micro-fluidic pipelines which are arranged side by side; the washing assembly comprises a washing liquid storage frame, a sliding guide rail and a waste liquid storage cavity, and a soft washing liquid bag is placed in the washing liquid storage frame; a pricking needle is fixedly arranged in the groove, one end of the sliding guide rail is connected to the washing liquid storage frame, the other end of the sliding guide rail is connected to the waste liquid storage cavity, and the sliding guide rail is tightly attached to the outer side of the fixing edge and can slide along the fixing edge; the sliding guide rail slides to drive the washing liquid storage frame and the waste liquid storage cavity to integrally slide in the groove. The device has the advantages of high cleaning efficiency, high detection sensitivity and high flux.

Description

technical field [0001] The invention relates to a microfluidic immunoassay combined detection device and a method for using the same, and belongs to the technical field of target object analysis and detection in biological materials. Background technique [0002] Lateral flow chromatography, also called lateral flow chromatography and lateral flow chromatography, is a new type of in vitro diagnostic technology developed in the 1990s on the basis of monoclonal antibody technology, colloidal gold immunochromatography technology and new material technology. , has the advantages of fast, simple, single-person detection, and economy, and has been widely used in medical testing, food quality monitoring, environmental monitoring, agriculture and animal husbandry, entry-exit inspection and quarantine, forensic judgment and other fields. [0003] Lateral flow chromatography uses a large-pore microporous membrane (NC membrane, nitrocellulose membrane) as a carrier to immobilize specif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/53B01L3/00
CPCG01N33/53B01L3/5027B01L2200/10
Inventor 徐恩良吴凤霞徐高扬
Owner XIAMEN XIANMING BIOTECH CO LTD
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