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Heat-stress-resistant traditional Chinese medicine and preparation method thereof

An anti-heat stress, traditional Chinese medicine technology, applied in the directions of pharmaceutical formulations, antidote, and drug combinations, can solve the problems of lack of anti-heat stress traditional Chinese medicine preparations, unsatisfactory anti-heat stress effects, and reduced bioavailability of traditional Chinese medicines. Achieve the effect of improving bioavailability, reducing adverse effects and high bioavailability

Active Publication Date: 2021-10-01
JIANGXI AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the anti-heat stress effects of these additives are not ideal enough, and sedative and antibiotic additives will also produce toxic side effects and drug residues. At present, most anti-heat stress Chinese herbal medicine additives are simply crushed Chinese herbal medicines and added in powder form, resulting in Decreased bioavailability of traditional Chinese medicine affects anti-heat stress effect
[0005] Anti-heat stress traditional Chinese medicines are divided into heat-clearing, anti-convulsant, metabolic-regulating, central nervous function-adjusting, and immune-enhancing classes. In the existing technology, there is still a lack of suitable anti-heat stress traditional Chinese medicine preparations for farmed animals. and the mechanism of action of anti-heat stress traditional Chinese medicine

Method used

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  • Heat-stress-resistant traditional Chinese medicine and preparation method thereof
  • Heat-stress-resistant traditional Chinese medicine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The invention provides an anti-heat stress traditional Chinese medicine, which is mainly prepared from the following materials in parts by weight: 3 parts of Pteris vulgaris, 3 parts of Huoxiang, 3 parts of Radix Ophiopogon japonicus, 3 parts of hawthorn, 3 parts of honeysuckle, and 3 parts of Jujube Seed 3 parts of gypsum, 3 parts of chrysanthemum, 3 parts of cork, and 3 parts of mint.

[0016] The inventor found in the research process that Chinese herbal medicines for clearing away heat and detoxification can improve the growth performance of animals, regulate the body's immunity and enhance the antioxidant function, and alleviate the impact of heat stress on animals. Heat stress damages intestinal structure and mucous membrane in mice; Hawthorn, Cortex Phellodendri, Patchouli and Pteris all have anti-inflammatory effects. Through further experiments and combined with modern pharmacological research, it was found that Pteris fragrans is light in taste, slightly bitte...

Embodiment 2

[0021] The main difference between Example 2 of the present invention and Example 1 is that: the anti-heat stress traditional Chinese medicine is mainly prepared from the following materials in parts by weight: 5 parts of Pteris vulgaris, 5 parts of Huoxiang, and 5 parts of Ophiopogon japonicus , 5 parts of hawthorn, 5 parts of honeysuckle, 5 parts of jujube seed, 5 parts of gypsum, 5 parts of chrysanthemum, 5 parts of cork, and 5 parts of mint.

[0022] The preparation method of the anti-heat stress traditional Chinese medicine, first, take all the materials used to prepare the anti-heat stress traditional Chinese medicine according to the weight ratio, a total of 50 parts, which is the weight of the crude drug, first rinse twice with clean water, and wash the Put the material in a casserole and soak it in distilled water for at least 1 hour, then boil it over high heat, then boil it over low heat for 1 hour, filter, take the filtrate, add distilled water to the filter residue...

Embodiment 3

[0025] The main difference between Example 3 and Example 2 of the present invention is that the anti-heat stress traditional Chinese medicine is mainly prepared from the following materials in parts by weight: 4 parts of Pteris vulgaris, 4 parts of Huoxiang, and 4 parts of Ophiopogon japonicus , 4 parts of hawthorn, 4 parts of honeysuckle, 4 parts of jujube seed, 4 parts of gypsum, 4 parts of chrysanthemum, 4 parts of Phellodendron cork, and 4 parts of mint.

[0026] The preparation method of the anti-heat stress traditional Chinese medicine, first, take all the materials used to prepare the anti-heat stress traditional Chinese medicine according to the weight ratio, a total of 40 parts, which is the weight of the crude drug, first rinse with clean water once, and wash the Put the material in a casserole and soak it in distilled water for 1 hour, then boil it over high heat, then boil it over low heat for 1 hour, filter, take the filtrate, add distilled water to the filter resi...

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Abstract

The invention discloses a heat-stress-resistant traditional Chinese medicine which is mainly prepared by adding radix ophiopogonis and semen ziziphi spinosae for calming, quieting the heart and promoting the secretion of saliva or body fluid on the basis of a traditional Chinese medicine compound consisting of five medicinal materials, namely wrinkled gianthyssop herb, gypsum, honeysuckle flower, chrysanthemum flower and herba menthae having the effect of clearing summer-heat, adding cortex phellodendri and herba pteridis multifidae for resisting inflammation and bacteria, and adding fructus crataegi for regulating digestion to prepare the heat-stress-resistant traditional Chinese medicine decoction. The invention also provides a preparation method of the heat-stress-resistant traditional Chinese medicine, and the heat-stress-resistant mechanism of the heat-stress-resistant traditional Chinese medicine is determined through experiments. The heat-stress-resistant traditional Chinese medicine can effectively improve the survival rate of animals under the high-temperature condition and reduce the adverse effect of heat stress on animal growth, and the action mechanism of the heat-stress-resistant traditional Chinese medicine is that the heat-stress-resistant capacity of the body is enhanced by adjusting the fever mechanism of the body, remarkably improving the blood cell condition and maintaining the stability of blood indexes in the body; reference is provided for later-stage heat-stress-resistant traditional Chinese medicine research and application of the heat-stress-resistant traditional Chinese medicine to animal breeding.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine formulas, in particular to an anti-heat stress traditional Chinese medicine formula and a preparation method thereof. Background technique [0002] Heat stress refers to the sum of non-specific responses made by humans and animals when they are stimulated by high temperature that exceeds their self-regulation ability. Due to the high summer temperature in southern my country, which lasts for a long time, and the rapid development of intensive animal husbandry farming methods, the heat stress caused by high temperature will cause changes in the physiological and biochemical processes in animals, which will adversely affect the health and production performance of livestock and poultry. Effects, causing metabolic disorders in animals, decreased production performance, weakened immunity, and even death. It brings huge losses to the breeding industry. Therefore, finding safe and effective m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P39/00A61K33/06
CPCA61K36/12A61K36/532A61K36/8968A61K36/734A61K36/355A61K36/725A61K33/06A61K36/287A61K36/756A61K36/534A61P39/00A61K2236/331A61K2236/39A61K2300/00Y02A50/30
Inventor 王小莺鲍光明郭小权刘宝生刘立恒凌丽芳
Owner JIANGXI AGRICULTURAL UNIVERSITY
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