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Preparation method of large-trauma chitosan hemostatic particles

A technology of hemostatic granules and chitosan, applied in the directions of pharmaceutical formulation, application, medical science, etc., can solve the problems of complex production process, high production cost, inability to stop bleeding, etc., and achieves simple production process, improved success rate, and low production cost. Effect

Pending Publication Date: 2021-10-22
重庆大清海德生物技术有限公司
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Problems solved by technology

[0004] However, in the prior art, the production process of the hemostatic granule is relatively complicated, and the production cost is high, and the hemostatic granule after production cannot quickly and effectively stop the bleeding of the user's wound, and cannot stop the bleeding of a larger wound. , leading to a low success rate of emergency rescue, for this reason, we proposed a preparation method of large trauma chitosan hemostatic particles

Method used

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  • Preparation method of large-trauma chitosan hemostatic particles

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Embodiment Construction

[0045] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0046] see figure 1 Shown, the present invention is a kind of preparation method of large wound chitosan hemostatic granule, comprises the following steps:

[0047] S1: purification, used to purify chitosan;

[0048] Here, purification consists of at least the following steps:

[0049] S101: mixing raw materials, adding chitosan into the sodium hydroxide solution at a ratio of 1:10 by weight, and the sodium hydroxide solution is 0.2mol / L;

[0050] S102: stirring...

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Abstract

The invention discloses a preparation method of large-trauma chitosan hemostatic particles, and relates to the technical field of hemostatic particles. The method comprises the following steps: purification: carrying out purification treatment on chitosan; drying: drying the purified chitosan; mixing and granulating: preparing the chitosan and the chitosan derivative into a granular material; freeze-drying: carrying out freeze-drying treatment on the granular materials until the granular materials are loose and porous granules; sieving and packaging: sieving and packaging the granular materials; performing sterilization; and performing external packaging. The chitosan hemostatic particles can be produced through cooperation of all the steps, the production process is simple, the production cost is low, the produced chitosan hemostatic particles can rapidly and effectively stop bleeding of wounds of users and can stop bleeding of large wounds, and the chitosan hemostatic particles are convenient to carry. and the success rate of emergency rescue is greatly improved.

Description

technical field [0001] The invention belongs to the technical field of hemostatic granules, in particular to a preparation method of chitosan hemostatic granules for large wounds. Background technique [0002] Hemostasis refers to the treatment of bleeding in a certain way to quickly stop the blood from flowing outward; [0003] When wars, natural disasters and major accidents occur, it is easy to cause greater trauma to the wounded, and the blood flow will not stop. When the blood left by the wounded is more, it will affect the life safety of the wounded. In order to treat the wounded, it is necessary to Emergency treatment of wounds of the wounded, hemostasis of wounds, and hemostatic particles are needed in the process of hemostasis; [0004] However, in the prior art, the production process of the hemostatic granule is relatively complicated, and the production cost is high, and the hemostatic granule after production cannot quickly and effectively stop the bleeding of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/08A61L24/00
CPCA61L24/08A61L24/0015A61L24/001A61L2400/04A61L2300/232A61L2300/418C08L5/08
Inventor 杜连晖蔺洪耀殷瑞贤黄方舒邹景燚张斌
Owner 重庆大清海德生物技术有限公司
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