Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance

A soft matter, volume ratio technology, applied in pharmaceutical formulations, medical preparations with inactive ingredients, emulsion delivery, etc., can solve the problem that the interface behavior of super-amphiphilic host-guest polymers has not been further studied, and achieve the realization of The effect of structural diversity and efficient interface stabilization

Pending Publication Date: 2021-10-26
HAINAN UNIVERSITY
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the tunable interfacial behavior of superamphiphilic host-guest polymers has not been further investigated

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance
  • Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance
  • Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Referring to the accompanying drawings, the present invention will be further described in conjunction with specific embodiments, so as to better understand the present invention. If no specific technique or condition is indicated in the examples, it shall be carried out according to the technique or condition described in the literature in this field or according to the product specification. The reagents or instruments used were not indicated by the manufacturer, and they were all commercially available conventional products.

[0034] 1. Synthesis of amphiphilic host molecule Alg-β-CD

[0035] Utilize mild Ugi reaction to synthesize amphiphilic polymer molecule Alg-β-CD, the steps are as follows:

[0036] Sodium alginate with a mass fraction of 2.5wt% was mechanically stirred at room temperature for 6h, diluted with water to a mass fraction of 2.0wt%, and the pH of the solution was adjusted to 3.6 with 0.5mol / L HCl solution, and formaldehyde (0.542mL ), cyclohexylis...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
Login to view more

Abstract

The invention provides a Pickering emulsion. The Pickering emulsion comprises an oil phase and a water phase, wherein the volume ratio of the oil phase is 4.2%-90%, Alg-beta-CD is dispersed in the water phase, and AzoC12 is dispersed in the oil phase. The invention further provides a super-amphiphilic host-guest alginate-based anisotropic structure soft substance prepared from the Pickering emulsion. A novel amphiphilic-controllable super-amphiphilic Alg-beta-CD/AzoC12 self-assembly is designed and prepared, has better interface adsorption performance and can be used for preparing a W/O/W emulsion with good stability by a phase inversion method. The amphipathy of the super-amphiphilic aggregate can be properly adjusted on the basis of host-guest action, an ideal and convenient strategy can be provided for phase separation behavior control of the host-guest multiphase emulsion, so that the structural diversity of the soft material is realized, and the Pickering emulsion has potential application value in colloidal materials.

Description

technical field [0001] The invention relates to a method for preparing a super-amphiphile host-guest alginate-based anisotropic soft material. Background technique [0002] Heterogeneous Pickering emulsions have great application potential in drug encapsulation, industrial production, and material science. In recent years, heterogeneous Pickering emulsions have been explored as ideal templates for interfacial self-assembly to achieve diverse morphologies of anisotropic structures. Due to the irreversible adsorption of interfacial stabilizers, colloidal nanoparticles-stabilized heterogeneous Pickering emulsions exhibit better stability, in sharp contrast to conventional surfactant-stabilized heterogeneous emulsions with different hydrophilic-hydrophobic balance (HLB). In addition, traditional multiphase emulsions not only require two emulsification steps, but also require a large amount of energy input to reduce the interfacial potential energy. In the formation mechanism o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/107A61K47/36C08B37/04C08B37/16
CPCA61K9/107A61K47/36C08B37/0084C08B37/0012
Inventor 李嘉诚冯玉红杨淑娟余高波
Owner HAINAN UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap