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Cancellous bone modeling method, device, storage medium and electronic equipment

A cancellous bone and model technology, applied in the field of medical image processing, can solve the problems of high cost, inability to be widely used, large radiation dose, etc., and achieve the effect of high applicability

Active Publication Date: 2022-04-22
TSINGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, high-resolution microCT technology has a large amount of radiation, and the maximum scanning resolution is 40-60 μm. Although a clear trabecular network structure can be observed, it is expensive and cannot be widely used.

Method used

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  • Cancellous bone modeling method, device, storage medium and electronic equipment
  • Cancellous bone modeling method, device, storage medium and electronic equipment
  • Cancellous bone modeling method, device, storage medium and electronic equipment

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Effect test

Embodiment 1

[0084] The present invention provides a cancellous bone modeling method, please refer to figure 1 , the method includes the following steps:

[0085] Step S110: Obtain a CT detection image of the target cancellous bone.

[0086] The target cancellous bone is the cancellous bone to be tested, and the CT detection image of the target cancellous bone is obtained by scanning a clinical TC image with a relatively low resolution. For example, the commonly used clinical CT technology for clinical observation of bone density differences has a small radiation dose, and the resolution of the CT detection image obtained by scanning is up to 0.6 mm.

[0087] Step S120: Establish an equivalent volume unit RVE model according to the CT detection image.

[0088] The equivalent volume element RVE model is also called the representative volume element (Representative VolumeElement, RVE) model. The RVE model consists of a large number of strengthening phases and matrix phases. Its scale is h...

Embodiment 2

[0095] On the basis of the first embodiment, this embodiment describes the method in the first embodiment through specific implementation cases.

[0096] In the above cancellous bone modeling method, before obtaining the cancellous bone model according to the RVE model and the pre-trained prediction model, the method also includes the following process: firstly obtain CT images of a plurality of sample bones, and Obtain the data of the plurality of sample bones. Among them, the multiple sample bones need to include samples of different genders, different parts and different ages, and the data of multiple sample bones are obtained from the database at the same time. The data of the sample bone include the elastic modulus of the trabecular bone of the sample bone and the mapping relationship between the elastic modulus of the trabecular bone and the unit circle for conformal mapping. Then, a three-dimensional finite element model and a three-dimensional pixel information matrix...

Embodiment 3

[0099] On the basis of the second embodiment, this embodiment describes the method in the first embodiment through specific implementation cases.

[0100] Before obtaining the data of the plurality of sample bones from the database, the database needs to be obtained first, which can be obtained according to the following method. Firstly, microscopic and nano-indentation experiments are carried out on the experimental sections of the plurality of sample bones to obtain the elastic modulus of trabecular bone corresponding to each of the sample bones, and then the trabecular bone modulus of the experimental sections of each of the sample bones is obtained. The mapping relationship between the elastic modulus of the beam and the unit circle is conformally mapped, and finally a database including the elastic modulus of the trabecular bone and the mapping relationship can be obtained.

[0101] Specifically, firstly, according to the conformal mapping method, the mapping relationship...

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Abstract

The present application relates to the technical field of medical image processing, in particular to a cancellous bone modeling method, device and electronic equipment, which solves the problems in the prior art. The method includes: first obtaining the CT detection image of the target cancellous bone, then processing the CT detection image, and establishing an equivalent volume unit RVE model that can accurately reflect the microstructure of the target cancellous bone according to the CT detection image, so as to ensure the follow-up The cancellous bone model can be quickly and accurately obtained according to the RVE model and the pre-trained prediction model, and the cancellous bone model can accurately represent the spatial distribution of mechanical parameters such as the microstructure and elastic modulus of the cancellous bone. In addition, the RVE model established according to the CT detection image has a certain degree of unity. Therefore, after the RVE model is established according to different CT detection images corresponding to different target cancellous bone, the cancellous bone can be obtained according to the pre-trained prediction model. Model, this method has high applicability for establishing cancellous bone model.

Description

technical field [0001] The present application relates to the technical field of medical image processing, in particular to a cancellous bone modeling method, device, storage medium and electronic equipment. Background technique [0002] The three-dimensional reconstruction of cancellous bone of human skeleton refers to the establishment of a three-dimensional digital model that can reflect the real bone structure through medical images, and is used to study the shape of the bone and the stress state under different motion states. At present, the reconstructed human skeleton model often stays at the level of trabecular bone. For example, the equivalent transversely isotropic material parameters of the cancellous bone structure can be given by establishing a homogenized continuous model. This type of method has a small amount of calculation and only requires clinical CT scans to obtain the distribution of bone density, but it must be assumed that the modulus is strongly corr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06T17/20G06N3/04G06N3/08G16H30/20
CPCG06T7/0012G06T17/20G06N3/08G16H30/20G06T2207/10081G06T2207/30008G06T2207/20081G06N3/045
Inventor 严子铭胡元裕刘冰川田耘柳占立庄茁
Owner TSINGHUA UNIV
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