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Pharmaceutical composition for cardiovascular and cerebrovascular diseases as well as preparation method and application thereof

A technology for cardiovascular and cerebrovascular diseases and compositions, which is applied in the field of pharmaceutical compositions and its preparation, and can solve problems such as the lack of specific medicines for treatment and health care, the lack of first aid and preventive health care functions, myocardial blood supply insufficiency, etc.

Pending Publication Date: 2021-12-14
北京孔氏中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, the incidence of myocardial infarction is still increasing gradually. The cause of acute myocardial infarction is coronary artery atherosclerosis, which causes one or more vessels to narrow the lumen and cause insufficient blood supply to the myocardium. At this time, the collateral circulation is not fully established. On this basis, once the blood supply is sharply reduced or interrupted, it will cause severe and persistent myocardial ischemia and hypoxia for more than 20-30 minutes, and acute myocardial infarction will occur. However, many patients have no signs of attack before.
And there is no drug product with effective first aid and preventive health care functions on the market at present, and there is a lack of specific drugs for treatment and health care.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0036] The present invention also provides a preparation method of the granule, the method is as follows: weighing each drug in proportion, grinding and crushing each raw material into powder, then soaking in water, heating and extracting, and then concentrating and purifying the drug solution to remove water and drying to obtain The drug granules are finally sealed and packaged for sterilization, and used as granules.

[0037] Preferably, the particle size range of grinding and crushing is 30-40 mesh. Add water soaking time for 24 hours or more. The granule is taken with warm water.

Embodiment 1

[0040] A pharmaceutical composition for cardiovascular and cerebrovascular diseases. The raw materials of the pharmaceutical composition include by weight: 2,500g of Nanshen, 300g of Angelica, 200g of Codonopsis, 300g of Radix Astragali, 200g of Tianma, 100g of Saffron, 500g of Salvia, and 200g of Rhodiola , Polygala 120g, Ophiopogon japonicus 120g, Gynostemma 260g, Turtle Shell 200g, Panax notoginseng 300g, Chuanqiong 500g.

[0041] This embodiment also provides the use of the pharmaceutical composition for cardiovascular and cerebrovascular diseases, and the pharmaceutical composition is used to prepare granules for patients with cardiovascular and cerebrovascular diseases.

[0042] This embodiment also provides the preparation method of the granule, weighing each drug in proportion, grinding and crushing each raw material into powder, and the particle size range of grinding and crushing is 30-40 mesh. Then soak in water for 24 hours or more. Then heating and extracting, co...

Embodiment 2

[0044] A pharmaceutical composition for cardiovascular and cerebrovascular diseases. The raw materials of the pharmaceutical composition include by weight: 300g of chinnan, 40g of angelica, 30g of codonopsis, 40g of astragalus, 30g of gastrodia elata, 15g of saffron, 60g of salvia miltiorrhiza, and 30g of rhodiola , Polygala 15g, Ophiopogon japonicus 15g, Gynostemma 30g, Turtle Shell 30g, Panax notoginseng 40g, Chuanqiong 60g.

[0045] This embodiment also provides the use of the pharmaceutical composition for cardiovascular and cerebrovascular diseases, and the pharmaceutical composition is used to prepare granules for patients with cardiovascular and cerebrovascular diseases.

[0046] This embodiment also provides the preparation method of the granule, weighing each drug in proportion, grinding and crushing each raw material into powder, and the particle size range of grinding and crushing is 30-40 mesh. Then soak in water for 24 hours or more. Then heating and extracting, ...

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Abstract

The invention discloses a pharmaceutical composition for cardiovascular and cerebrovascular diseases as well as a preparation method and application thereof. The pharmaceutical composition is prepared from the following raw materials: Chinese magnoliavine, radix angelicae sinensis, radix codonopsis pilosulae, radix astragali, rhizoma gastrodiae, saffron crocus, radix salviae miltiorrhizae, rhodiola rosea, radix polygalae, radix ophiopogonis, gynostemma pentaphyllum, turtle shell, radix notoginseng and rhizoma Chuanxiong. The invention also provides the application of the pharmaceutical composition. The pharmaceutical composition is used for preparing dissolved granules taken by patients with the cardiovascular and cerebrovascular diseases. The invention also provides a preparation method of the dissolved granules. According to the pharmaceutical composition for the cardiovascular and cerebrovascular diseases and the preparation method and application thereof, the pharmaceutical composition has the characteristics of being reasonable in formula, small in dosage, remarkable in effect, free of toxic and side effects, capable of taking effect rapidly and the like, and the prepared dissolved granules can be used for treating or preventing various cardiovascular and cerebrovascular diseases or applied to emergency treatment on sudden cardio-cerebral conditions.

Description

technical field [0001] The present invention relates to a pharmaceutical composition and its preparation method and application, in particular to a pharmaceutical composition for cardiovascular and cerebrovascular diseases, its preparation method and application. Background technique [0002] With the development of economy and society and the change of people's lifestyle, the incidence of cardiovascular disease has increased year by year. Cardiovascular death accounts for the first cause of death among urban and rural residents, and more than half of the people who die from cardiovascular disease each year die. in myocardial infarction. According to relevant statistics, the mortality rate caused by myocardial infarction has increased significantly in recent years, and the mortality rate of sudden myocardial infarction is as high as 11.9%, which has become a major disease with the highest fatality rate except cancer. [0003] Epidemiological surveys in recent years have sho...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/00A61P9/10A61P9/06A61K35/586
CPCA61K36/835A61K36/232A61K36/344A61K36/481A61K36/8988A61K36/88A61K36/537A61K36/41A61K36/69A61K36/8968A61K36/424A61K35/586A61K36/258A61K36/236A61P9/00A61P9/10A61P9/06A61K2236/15A61K2236/331A61K2236/51A61K2300/00
Inventor 孔庆博
Owner 北京孔氏中医院
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