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Composition for preventing or treating sars coronavirus 2 infection disease

A technology for respiratory syndrome and coronavirus, applied in respiratory diseases, drug combinations, antiviral agents, etc., can solve the problems of unpublished prevention or treatment of coronavirus infection, and achieve the effect of preventing or improving the diseases caused by

Pending Publication Date: 2021-12-21
シンテカバイオ インコーポレイティッド
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] As technologies related to pharmaceutical compositions for improving or treating coronavirus infections, Korean Patent No. 1913789 discloses compounds for treating diseases caused by coronavirus infections, and U.S. Laid-Open Patent No. 2006-0257852 discloses Technology related to severe acute respiratory syndrome coronavirus, but does not disclose the composition of the present invention for preventing or treating coronavirus infection, which contains the activity inhibitor of coronavirus 3CL protease as an active ingredient

Method used

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  • Composition for preventing or treating sars coronavirus 2 infection disease
  • Composition for preventing or treating sars coronavirus 2 infection disease
  • Composition for preventing or treating sars coronavirus 2 infection disease

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0102] Preparation example 1. Zafirlukast (Zafirlukast)

[0103] Commercially available zafirlukast (CAS Number: 107753-78-6) was used.

preparation example 2

[0104] Preparation example 2. Sulfinpyrazone (Sulfinpyrazone)

[0105] Commercially available sulfinpyrazone (CAS Number: 57-96-5) was used.

preparation example 3

[0106] Preparation example 3. Combined use of zafirlukast and sulfinpyrazone

[0107] The above-mentioned zafirlukast and sulfinpyrazone are used in combination.

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PUM

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Abstract

Disclosed is a pharmaceutical composition for preventing or treating severe acute respiratory syndrome coronavirus 2 infection disease, the composition comprising a compound represented by a Chemical Formula 1, or a pharmaceutically acceptable salt thereof, as an active ingredient.

Description

technical field [0001] The present invention relates to a composition for preventing or treating severe acute respiratory syndrome coronavirus 2 infection or diseases caused by severe acute respiratory syndrome coronavirus 2 infection. Background technique [0002] Severe acute respiratory syndrome coronavirus 2 is also known as COVID-19, SARS-CoV-2, 2019-nCoV virus. The World Health Organization (WHO) declared a public health emergency of international concern (PHEIC) in response to COVID-19, and on March 11, 2020, declared COVID-19 as a follow-up to Hong Kong influenza (1968) and influenza A (H1N1) (2009). global pandemic. COVID-19 is transmitted when droplets (saliva) from an infected person penetrate the respiratory tract or the mucous membranes of the eyes, nose and mouth. And when infected, after an incubation period of 2 to 14 days (estimated), respiratory symptoms such as fever, cough or dyspnea, and main symptoms such as pneumonia will appear, but occasionally asy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4152A23L33/10A23L2/52A23F3/16A23F3/14A61P11/00A61P31/14C12G3/05A61K31/4045
CPCA61K31/4045A61K31/4152A61P31/14A61P11/00A23L33/10A23L2/52A23F3/14A23F3/163C12G3/05A23V2002/00A61K2300/00A23V2200/314A61K31/404A23V2200/324A23V2250/30A61K31/405A61K9/0073A61K9/0053A61K9/0043
Inventor 郑钟善洪宗喜金东明朴奉焕柳永培权亨俊李仁哲朴智英
Owner シンテカバイオ インコーポレイティッド
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