Antibiotic-free feed additive for preventing and controlling calf diarrhea as well as preparation method and use method of antibiotic-free feed additive

Abstract

The invention discloses an antibiotic-free feed additive for preventing and controlling calf diarrhea as well as a preparation method and a use method of the antibiotic-free feed additive, and relates to the antibiotic-free feed additive for preventing and controlling the calf diarrhea as well as the use method of the antibiotic-free feed additive. The invention aims to solve the technical problems that in the current prevention and control of calf diarrhea, the drug resistance of bacteria is gradually increased, beneficial microorganisms in digestive tracts can be inhibited or killed by using antibiotics, intestinal flora imbalance is caused, the resistance of calves is reduced, visceral organs such as livers and kidneys are damaged, and the illness state is aggravated. The sodium humate and the attapulgite powder have high adsorption capacity, and can effectively inhibit reproduction of enteropathogenic bacteria and adsorb toxins generated by the enteropathogenic bacteria; glutamine provides energy for proliferation and development of intestinal epithelial cells; and the xylooligosaccharide and the probiotics can regulate the intestinal microenvironment, improve the intestinal flora, increase the intestinal probiotics and reduce the number of intestinal pathogenic bacteria. Therefore, the product can effectively prevent and control calf diarrhea by improving the physical barrier and the biological barrier of the calf intestinal tract to protect the intestinal tract health.

Description

technical field [0001] The invention relates to an antibiotic-free feed additive for preventing and controlling calf diarrhea and its application method. Background technique [0002] In recent years, with the improvement of the modernization and intensive production of my country's cattle industry, calf diarrhea has gradually become the main disease affecting the cattle industry. One of the main factors of ill health and death. Calf diarrhea refers to a disease characterized by diarrhea in calves during lactation and before and after weaning due to the influence of various internal and external factors. The clinical manifestations are loose stools, watery stools, loss of appetite, depression and dehydration. The disease can occur throughout the year, with the highest incidence of newborn calves within 3 weeks of age, and easily secondary to other diseases, causing serious economic losses to the cattle industry. [0003] The occurrence of calf diarrhea is caused by many fac...

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Problems solved by technology

[0003] The occurrence of calf diarrhea is caused by many factors, mainly including: (1) The calf’s digestive system is not fully developed, and the activity of gastric acid and gastrointestinal digestive enzymes is low. In addition, the leftover milk or feeding Feeding feed that is not fresh or even moldy can easily lead to digestive system disorders of calves, causing diarrhea; (2) The sanitary conditions of the pens are poor, and mildewed bedding is used or the bedding is not replaced in time to cause pathogenic microorganisms and parasites Massive breeding, coupled with weak resistance of calves, can easily cause calves infection and cause diarrhea; (3) Over-eating concentrates can also cause calves diarrhea

[0004] At present, the prevention and control of calf diarrhea mainly relies on antibiotics and chemically synthesized drugs. These drugs are effective in the treatment of diarrhea caused by bacteria. However, with the widespread use of antibiotics, bacterial drug resistance is gradually increasing, resulting in a narrower range of drug selection.

In addition, for diarrhea caused by non-pathogenic microorganisms such as stress and nutrition, antibiotic treatment is generally ineffective. The use of antibiotics will also inhibit or kill beneficial microorganisms in the digestive tract, causing intestinal flora imbalance, reducing the resistance of calves, and damaging the liver. Kidneys and other organs lead to aggravation of the disease, which increases the mortality rate

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