Combination medicine for treating condyloma acuminatum as well as preparation method and use method of combination medicine

The technology of condyloma acuminatum and medicine is applied in the field of combination medicine for the treatment of condyloma acuminatum and its preparation field, which can solve the problems of HPV virus recurrence, adverse reactions, low curative effect and the like, and achieves the advantages of promoting wound healing, reducing the recurrence rate and good bacteriostatic performance. Effect

Pending Publication Date: 2022-03-11
GUANGXI XINYE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The medicines currently on the market for the treatment of condyloma acuminatum generally have poor curative effect and are very prone to relapse after treatment and have serious adverse reactions. For example, CN02153460.8 provides a combination drug for the treatment of condyloma acuminata and a preparation method thereof. The combination drug consists of Composed of Sophora flavescens, salicylic acid, podophyllotoxin and borneol, the curative effect of this combination drug is low, it cannot effectively kill the HPV virus in the deep layer of the skin, and it is easy to cause recurrence. The salicylic acid, podophyllotoxin and borneol in this composition are all skin irritations Active ingredients may cause serious adverse reactions when in contact with normal skin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] A combination medicine for treating condyloma acuminatum, the combination medicine includes two parts of a wart removal agent and a protective agent used in conjunction with each other, the wart removal agent is a gel, and the protective agent is a spray, specifically:

[0063] The anti-wart agent is made up of the following raw materials in weight percentage:

[0064] Podophyllotoxin Imiquimod Cantochelin Complex Nano-Liposome 5%

[0065] Brucea javanica extract 5%

[0066] Carbomer 2%

[0067] Triethanolamine 2%

[0068] 1,2 pentanediol 3%

[0069] Glycerin 10%

[0070] Purified water 73%;

[0071] Protective agent is made up of the raw material of following percentage by weight:

[0072] Anti-HPV egg yolk antibody recombinant human α-2b interferon complex nano-liposome 3%

[0073] Green Tea Extract 2%

[0074] Carboxymethyl Chitosan 2%

[0075] 1,2 pentanediol 3%

[0076] Purified water 90%.

[0077] The preparation method of the combination medicine for t...

Embodiment 2

[0109] A combination medicine for treating condyloma acuminatum, the combination medicine includes two parts of a wart removal agent and a protective agent used in conjunction with each other, the wart removal agent is a gel, and the protective agent is a spray, specifically:

[0110] The anti-wart agent is made up of the following raw materials in weight percentage:

[0111] Podophyllotoxin Imiquimod Cantochelin Complex Nano-Liposome 6%

[0112] Brucea javanica extract 4%

[0113] Carbomer 2%

[0114] Triethanolamine 1%

[0115] 1,2 pentanediol 2%

[0116] Glycerin 5%%

[0117] Purified water 80%;

[0118] Protective agent is made up of the raw material of following percentage by weight:

[0119] Anti-HPV egg yolk antibody recombinant human α-2b interferon complex nano-liposome 4%

[0120] Green Tea Extract 6%

[0121] Carboxymethyl Chitosan 3%

[0122] 1,2 pentanediol 2%

[0123] Purified water 85%.

[0124] The preparation method of the combination medicine for t...

Embodiment 3

[0156] A combination medicine for treating condyloma acuminatum, the combination medicine includes two parts of a wart removal agent and a protective agent used in conjunction with each other, the wart removal agent is a gel, and the protective agent is a spray, specifically:

[0157] The anti-wart agent is made up of the following raw materials in weight percentage:

[0158] Podophyllotoxin Imiquimod Cannochelin Complex Nano-Liposome 10%

[0159] Brucea javanica extract 3%

[0160] Carbomer 1%

[0161] Triethanolamine 1%

[0162] 1,2 pentanediol 1%

[0163] Glycerin 5%

[0164] Purified water 79%;

[0165] Protective agent is made up of the raw material of following percentage by weight:

[0166] Anti-HPV egg yolk antibody recombinant human α-2b interferon composite nano-liposome 6%

[0167] Green Tea Extract 10%

[0168] Carboxymethyl Chitosan 4%

[0169] 1,2 pentanediol 2%

[0170] Purified water 78%.

[0171] The preparation method of the combination medicine fo...

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PUM

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Abstract

The invention relates to the technical field of condyloma acuminatum, in particular to a combined medicine for treating condyloma acuminatum and a preparation method and a using method thereof.The medicine is divided into a wart removing agent and a protective agent which are used in cooperation, warts can be rapidly removed, irritation of the medicine can be reduced, normal skin near the warts can be protected, wound healing is promoted, and the effect of treating the condyloma acuminatum is achieved. The wart removing agent is a gel, composite powerful wart removing components such as podophyllotoxin, imiquimod, cantharidin and a brucea javanica extract are added, and when the gel is smeared on a wart body of condyloma acuminatum, wart cell apoptosis can be rapidly induced, so that the wart body rapidly falls off; the protective agent is a spray, effective components such as an anti-HPV egg yolk antibody (IGY), recombinant human alpha-2b interferon and a green tea extract are added, the IGY can specifically kill HPV viruses, the recombinant human alpha-2b interferon and the green tea extract can stimulate proliferation of immunosuppressive viruses, the various components are matched to thoroughly remove the HPV viruses on the skin, and the recurrence rate is greatly reduced.

Description

technical field [0001] The invention relates to the technical field of treating condyloma acuminatum, in particular to a combined medicine for treating condyloma acuminatum and its preparation method and application method. Background technique [0002] Genital warts are a sexually transmitted disease. It mostly occurs in young and middle-aged people aged 18 to 50. Condyloma acuminatum is caused by human papillomavirus (HPV) infection, with hyperplastic lesions in the anogenital area as the main manifestation. Condyloma acuminatum will appear in the early stage with small cone-shaped small fleshy papules, which usually occur on the external genitalia and perianal area. Most of them are pink and vegetable. The surface is very brittle and can be easily removed by hand. The incubation period of genital warts varies from person to person, generally ranging from 2 weeks to 10 months, with an average of 3 months. Individual long also has about 12 months. The incidence of condy...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K31/365A61K31/4745A61K31/381A61K39/42A61K38/21A61K36/82A61K31/722A61K47/36A61K47/10A61K47/32A61K9/06A61K9/12A61K9/127A61P31/20A61P15/00A61P17/02
CPCA61K36/185A61K31/365A61K31/4745A61K31/381A61K39/42A61K38/212A61K36/82A61K31/722A61K47/36A61K47/10A61K47/32A61K9/06A61K9/0014A61K9/1271A61K9/1277A61P31/20A61P15/00A61P17/02A61K9/12A61K2300/00
Inventor 林福明雷艳梁文棋梁奕福李艺华陈春侨陈晶晶余勇华韦梦晓
Owner GUANGXI XINYE BIOLOGICAL TECH
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