Preparation method and process of compound paclitaxel anti-leukemia capsule tablet

Abstract

The invention provides a preparation method and process of a compound paclitaxel anti-leukemia capsule tablet. The compound paclitaxel anti-leukemia capsule tablet is prepared from the following medicinal compositions aiming at acute lymphocytic leukemia: astragalus membranaceus, codonopsis pilosula, liquorice, asparagus cochinchinensis, roasted rhizoma polygonati, fructus lycii, angelica sinensis, radix paeoniae alba, hairyvein agrimony, eclipta alba, lalang grass rhizome, lithospermum, radix scrophulariae, isatis root, folium isatidis, pericarpium papaveris, gypsum, ornithogalum caudatum saponin, papaya alkaloid and antrodia camphorata polysaccharide. The composition is prepared from the following raw materials: SOD, fiveleaf gynostemma herb and compound paclitaxel. The agent A and the agent B contain various compounds such as saponins, terpenoids, alkaloids, flavonoids, sterols and polysaccharides, drug molecules are micronized and can be fully absorbed and utilized after the agent A and the agent B are prepared through magnetized water and ultrasonic oscillation, and under the synergistic effect of all the drugs, the effects of clearing away heat and toxic materials, cooling blood, nourishing yin, promoting salivation, stopping bleeding and regulating the spleen and the stomach are outstanding, the effect is fast, and the treatment effect is good. The symptom can be relieved after the medicine is taken for 1 hour.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a preparation method and technology of compound paclitaxel anti-leukemia capsule tablets. Background technique [0002] Leukemia is a malignant clonal disease of hematopoietic stem cells. Clonal leukemia cells proliferate and accumulate in bone marrow and other hematopoietic tissues due to mechanisms such as uncontrolled proliferation, differentiation disorder, and apoptosis inhibition, and infiltrate other non-hematopoietic tissues and organs, while inhibiting normal hematopoietic function. Clinically, different degrees of anemia, hemorrhage, infection, fever, enlargement of liver, spleen, lymph nodes and bone pain can be seen. [0003] In recent years, although there have been many effective methods for the treatment of leukemia, and some clinical results have been obtained, there are also many disadvantages, such as: radiotherapy and chemothe...

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Problems solved by technology

[0003] In recent years, although there have been many effective methods for the treatment of leukemia, and some clinical results have been obtained, there are also many disadvantages, such as: radiotherapy and chemotherapy have high toxicity and side effects, which often cause many complications and bring unnecessary pain to patients. ; Although bone marrow transplantation can save the lives of patients, it is difficult to match the bone marrow, and the rejection reaction is relatively strong. Many leukemia patients often die from the above reasons; after many patients take anti-leukemia chemotherapy drugs, their condition has been partially relieved or Controlled, but chances of recurrence remain high

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