Preparation method of glucosamine composite functional tablet

A functional and tablet technology, which is applied in the field of preparation of glucosamine compound functional tablets, can solve the problems of easy oxidation and discoloration of amino groups, single nutrient composition, and unreasonable dosage, so as to increase the content of glucosamine and increase nutrition and health care Function, effect of improving bioavailability

Pending Publication Date: 2022-04-15
JIANGSU ALAND NOURISHMENT
View PDF18 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] As a drug, glucosamine has many disadvantages, such as glucosamine is highly hygroscopic, and its amino group is easily oxidized and discolored. Therefore, the preparation requirements of glucosamine are relatively high, such as tablets need to be coated, packed in ampoules, and capsules should The shell is sealed and requires protection from moisture and oxygen
In addition, most of the commercially available glucosamine products have less effective drug content, poor stability, and low bioavailability. At present, there are many kinds of products for osteoarthritis, bone damage or osteoporosis in the domestic and foreign markets, and the quality varies. Qi, the existing dietary supplements on the market more or less have problems such as single nutrient composition, unreasonable composition and matching ratio, or unreasonable dosage, which leads to the inability of various functional ingredients to be well absorbed in the human body And use, can not achieve the ideal repair and treatment effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of glucosamine composite functional tablet

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] The invention provides a preparation method of an ammonia sugar composite functional tablet, comprising the following steps:

[0027] S1. Mix D-glucosamine hydrochloride, turmeric extract, and povidone K30 to form a mixture A, mix povidone K90 with water to prepare a slurry with a concentration of 5%, mix the mixture A into the slurry, and fully Dissolve until clear and transparent, put the obtained mixed material into a wet granulator, stir and mix to obtain the glucosamine hydrochloride turmeric extract granules;

[0028] S2. Mix the frankincense extract, calcium carbonate, and hypromellose to obtain a mixture B, prepare a slurry with a concentration of 1% with an appropriate amount of water and hypromellose, mix the mixture B into the slurry, and fully dissolve until it is clear and transparent, put the obtained mixed material into a wet granulator, stir and mix evenly, and obtain frankincense extract granules through wet granulation;

[0029] S3. Combine the glucos...

Embodiment 1

[0036] The preparation of the compound functional ingredient dosage form of glucosamine comprises the following steps:

[0037] 1) Prepare glucosamine hydrochloride turmeric extract granules; mix 77.6wt% D-glucosamine hydrochloride, 20wt% turmeric extract, and 2wt% povidone K30 to obtain mixture A. Prepare 0.4wt% povidone K90 with an appropriate amount of water to make a slurry with a concentration of 5wt%, fully dissolve the mixture A into the slurry until it is clear and transparent, put the obtained mixed material into a wet granulator, stir for 10 minutes, and mix well , to obtain glucosamine hydrochloride turmeric extract granules.

[0038] 2) Wet granulation of Boswellia extract: Mix 52 parts by weight of Boswellia extract, 47 parts by weight of calcium carbonate, and 1 part by weight of hypromellose to obtain a mixture B. Prepare hypromellose with an appropriate amount of water to form a slurry with a concentration of 1 wt%, fully dissolve the mixture B into the slurry...

Embodiment 2

[0043] 1) Preparation of glucosamine hydrochloride turmeric extract granules: Mix 77.6wt% D-glucosamine hydrochloride, 20wt% turmeric extract, and 2wt% povidone K30 to obtain mixture A. Prepare 0.4wt% povidone K90 with an appropriate amount of water to make a slurry with a concentration of 5wt%, fully dissolve the mixture A into the slurry until it is clear and transparent, put the obtained mixed material into a wet granulator, stir for 10 minutes, and mix well , to obtain glucosamine hydrochloride turmeric extract granules.

[0044] 2) Wet granulation of Boswellia extract: Mix 52 parts by weight of Boswellia extract, 47 parts by weight of calcium carbonate, and 1 part by weight of hypromellose to obtain a mixture B. Prepare hypromellose with an appropriate amount of water to form a slurry with a concentration of 1 wt%, fully dissolve the mixture B into the slurry until it is clear and transparent, put the obtained mixed material into a wet granulator, stir for 5 minutes, and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method of a glucosamine composite functional tablet, which comprises the following steps: preparing glucosamine hydrochloride turmeric extract particles, and then preparing frankincense extract particles; fully mixing glucosamine hydrochloride turmeric extract particles and frankincense extract particles with sodium chondroitin sulfate, aesculus chinensis extract, black pepper extract, vitamin C, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, polyvinylpolypyrrolidone and magnesium stearate, and pressing into tablets; and finally, coating the tablets to obtain the tablets. According to the invention, Chinese and western medicines are adopted to form a compound, the components and contents are selected, and the bioavailability is enhanced and the anti-inflammatory and disinfection effects are greatly enhanced by utilizing the direct synergistic effect of all the components.

Description

technical field [0001] The present invention is a divisional application of the invention application (202011599893.8). The invention belongs to the field of food technology, and in particular relates to a preparation method of an ammonia sugar compound functional tablet. Background technique [0002] Osteoarthropathy, as a stubborn disease, is afflicting countless patients, and it is urgent to prevent and treat osteoarthrosis. As a dietary supplement with a wide range of sources, glucosamine and chondroitin sulfate have preventive and therapeutic effects on osteoarthritis in middle-aged and elderly people and some special populations. Glucosamine can reduce the concentration of pro-inflammatory transcription factors, enhance the toughness of specific parts of cartilage, and prevent collagen denaturation by inhibiting the activity of hydrolytic enzymes and reducing the oxidation of lipids and proteins. Glucosamine can improve the metabolic function and nutrient absorption ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/125A23L33/10A23L33/105A23L33/15A23P10/28
CPCA23L33/125A23L33/10A23L33/105A23L33/15A23P10/28A23V2002/00A23V2200/30A23V2200/306A23V2250/2112A23V2250/21A23V2250/51084A23V2250/51088A23V2250/708
Inventor 陈洋张国栋贺庆夏旭东张兴张勇
Owner JIANGSU ALAND NOURISHMENT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap