Construction method of noninvasive differential diagnosis model for tuberculous and cancerous pleural effusion

A technology for pleural effusion and differential diagnosis, applied in the medical field, can solve the problems of slow diagnosis efficiency and low diagnosis accuracy, and achieve the effects of high accuracy, enhanced integrity and low cost

Pending Publication Date: 2022-07-01
XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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Problems solved by technology

[0002] The identification of benign and malignant pleural effusions is a common focus and difficulty in clinical practice, among which the identification of tuberculous and lung cancer pleural effusion is very important. Diagnosis is based on clinical signs, and the diagnostic accuracy is low. Therefore, a variety of examinations are needed to assist the diagnosis, such as routine pleural effusion, biochemical examinations, and thoracentesis is an important measure to extract pleural effusion for routine biochemical examinations. However, thoracentesis has a certain risk of complications for patients, and the diagnostic efficiency is slow. Therefore, it is necessary to design a method for constructing a non-invasive differential diagnosis model for tuberculous and cancerous pleural effusions, and to solve the above problems through the non-invasive differential diagnosis model.

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  • Construction method of noninvasive differential diagnosis model for tuberculous and cancerous pleural effusion

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Embodiment 1

[0020] see figure 1 , the present invention provides the following technical solutions: a method for constructing a non-invasive differential diagnosis model of tuberculous and cancerous pleural effusion, comprising the following steps:

[0021] S1: Using traditional Unet as the basic skeleton, adding three-dimensional attention mechanisms to build a class of deep learning models;

[0022] S2: Input the entire CT image into the deep learning model, and the deep learning model extracts the feature information of the entire CT image to obtain GlobalLoss. Based on the accuracy of GlobalLoss, update the parameters of a class of deep learning models until the accuracy rate reaches 95 % or more, a second-class deep learning model is obtained;

[0023] S3: Crop the 3D data of the entire CT image into 32×32×32 small image 3D data, and then input the small image 3D data into the second-class deep learning model for training, and update the second-class depth based on the accuracy Lea...

Embodiment 2

[0027] The difference between this embodiment and Embodiment 1 is:

[0028] Specifically, in step S5, the results diagnosed by the non-invasive differential diagnosis model for tuberculous and cancerous pleural effusion are stored in a folder for doctors to use as samples for normal human diagnosis training.

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Abstract

The invention discloses a construction method of a tuberculous and cancerous pleural effusion non-invasive differential diagnosis model, and belongs to the technical field of medicine, and the method comprises the following steps: S1, constructing a deep learning model; s2, constructing a second-class deep learning model; s3, constructing three types of deep learning models; s4, constructing a four-class deep learning model; s5, constructing a five-class deep learning model; according to the method, a traditional Unet is taken as a basic skeleton, a deep learning model is constructed by adding a three-dimensional attention mechanism, the segmentation performance of the model is trained through a cut local CT image, the classification performance of the model is trained through an overall CT image and the segmented local CT image, and finally the diagnosis model is obtained. The constructed diagnosis model can realize differential diagnosis only through CT images during diagnosis, has the advantages of low cost, non-invasiveness and high accuracy, reduces the risk of complications of patients, reduces the medical cost, improves the diagnosis efficiency, and effectively relieves the pressure of clinical workers.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a method for constructing a non-invasive differential diagnosis model of tuberculous and cancerous pleural effusion. Background technique [0002] The identification of benign and malignant pleural effusion is a common focus and difficulty in clinical practice, among which the identification of tuberculous and lung cancer pleural effusion is very important. The diagnosis is based on pleural effusion, clinical signs, and the diagnostic accuracy is low. Therefore, a variety of examinations are needed to assist the diagnosis, such as routine pleural effusion and biochemical examination methods. However, thoracentesis exposes patients to a certain risk of complications, and the diagnostic efficiency is slow. Therefore, it is necessary to design a method for constructing a non-invasive differential diagnosis model of tuberculous and cancerous pleural effusion, and to solve the above ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/10G06T7/00G06V10/764G06K9/62
CPCG06T7/0012G06T7/10G06T2207/10081G06T2207/30096G06T2207/30061G06T2207/20081G06T2207/20084G06F18/241
Inventor 金阳汪速飞谭学耘夏慧王智慧杨炼鲍庆嘉李丕强范茜茜陈文娟梁梦圆刘宇
Owner XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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