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Membrane-free dialysis micro-fluidic chip with parallel structure

A microfluidic chip and dialysate technology, applied in dialysis systems, blood circulation treatment, etc., can solve the problems of increasing dialysis efficiency, low efficiency, cell loss, etc., and achieve the effect of increasing working capacity and reducing volume

Pending Publication Date: 2022-07-05
UNIV OF SCI & TECH OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In addition to solving the problem of low efficiency and large cell loss in existing dialysis, the membraneless dialysis microfluidic chip can effectively increase the dialysis efficiency and reduce the loss of blood cells. It also uses its parallel honeycomb network structure to increase the working capacity of the chip, and The purpose of reducing the volume of artificial kidney and increasing the utilization efficiency of dialysate

Method used

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  • Membrane-free dialysis micro-fluidic chip with parallel structure
  • Membrane-free dialysis micro-fluidic chip with parallel structure

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Embodiment Construction

[0022] The present invention will be further described with reference to the accompanying drawings.

[0023] This embodiment discloses a membraneless dialysis microfluidic chip with a parallel structure, such as figure 1 and figure 2 As shown, a plurality of dialysis assemblies are included, and the plurality of dialysis assemblies are arranged in parallel, and the dialysis assemblies alternately form a cleaning section 3 and a separation section 4 along the direction of blood flow; the dialysis assembly includes a blood channel and a dialysate channel, the The blood channel and the dialysate channel meet in the cleaning section 3, and are separated in the separation section 4; during the cleaning section 3, the blood and the dialysate contact in the center of the cleaning section 3 channel, and when entering the next cleaning section 3, The contact surface of blood and dialysate is the outer fluid of the previous cleaning section 3 . Among them, the blood inlet 1, the dial...

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Abstract

The invention discloses a membrane-free dialysis micro-fluidic chip with a parallel structure, which comprises a plurality of dialysis assemblies, the dialysis assemblies are arranged in parallel, and the dialysis assemblies alternately form a cleaning section and a separation section along the blood flowing direction; the dialysis assembly comprises a blood channel and a dialysate channel, and the blood channel and the dialysate channel meet in the cleaning section and are separated in the separation section; in the cleaning section, blood and dialysate make contact in the center of a cleaning section channel, and when the blood and the dialysate enter the next cleaning section, the contact face of the blood and the dialysate is the outer side fluid of the previous cleaning section. According to the membrane-free dialysis micro-fluidic chip, the problems of low efficiency and large cell loss of existing dialysis are solved, the dialysis efficiency is effectively improved, the loss of blood cells is reduced, the parallel honeycomb network structure of the membrane-free dialysis micro-fluidic chip is utilized, the purposes of improving the working capacity of the chip and reducing the volume of an artificial kidney are achieved, and the utilization efficiency of dialysate is improved.

Description

technical field [0001] The invention relates to a membraneless dialysis microfluidic chip with a parallel structure. Background technique [0002] At present, there are nearly 800,000 dialysis patients in my country. With the acceleration of aging in my country, the continuous improvement of dialysis quality and dialysis treatment rate, and the improvement and improvement of medical insurance, the number of dialysis patients continues to increase at a rate of about 10% per year. The number of patients requiring dialysis treatment will exceed 3 million by 2030. Dialysis is one of the effective measures to prolong the life of patients and improve the quality of life of advanced patients. Hemodialysis machine, commonly known as "artificial kidney", is an extracorporeal hemodialysis device that can replace part of the kidney function, remove harmful substances in the blood, correct electrolytes in the body and maintain acid-base balance. [0003] Most of the existing dialysis d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/14A61M1/36
CPCA61M1/14A61M1/3692A61M1/3621
Inventor 林垚何立群程晓舫
Owner UNIV OF SCI & TECH OF CHINA