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Capsule for treating coryza and its preparation method

A technology of Ganmao capsules and oral medicines, applied in the field of medicine Ganmao capsules and its preparation, which can solve the problems of large doses, affecting effectiveness, and quality standards.

Inactive Publication Date: 2006-05-03
XINJIANG CICONHABO UYGUR MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The original dosage form of Zukamu is granules, the dosage is large, 12 grams at a time, three times a day, and it contains more sucrose, which is restricted for many elderly people and patients who are forbidden from sugar. process, but there is no inclusion, and the volatile oil is still volatilized, so there is no volatile oil in the finished product, which affects the effectiveness of the drug. The quality standard of the drug only stays on the two thin-layer identification indicators, which cannot represent the variety the inner quality of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0163] a. Put 8 parts of mint, 1 part of kaempferen, and 2 parts of chamomile into the extraction tank, add 6 times the amount of water to soak for 4 hours, extract the volatile oil for 3 hours, filter the distilled aqueous solution for later use, collect the volatile oil, and use 1 Add 5 g of β-cyclodextrin to 1 ml of volatile oil, stir at 30°C for 1 hour, refrigerate overnight, filter with suction, dry at 40°C for 2 hours, grind finely, pass through a 120-mesh sieve for later use; add 6 times the amount of water to the dregs Decoct for 1 hour, filter, and combine the filtrate with the distilled aqueous solution for later use;

[0164] b. Add 4 parts of jujube, 0.5 part of licorice, 3 parts of water lily, 2 parts of ragwort, 1 part of hollyhock seed, 1 part of rhubarb, 1 part of poppy husk and add 4 times the amount of Qiwei herbs to decoct 3 times , 1 hour each time, combine the decoction, filter, combine the filtrate with the standby solution, concentrate under reduced pres...

Embodiment 2

[0168] a. Put 10 parts of peppermint, 2 parts of kaempferen, and 3 parts of chamomile into the extraction tank, add 9 times the amount of water to soak for 4 hours, extract the volatile oil for 6 hours, filter the distilled aqueous solution for later use, collect the volatile oil, and use 1 Add 5 g of β-cyclodextrin to one milliliter of volatile oil, stir at 30°C for 1 hour, refrigerate overnight, filter with suction, dry at 40°C for 5 hours, grind finely, pass through a 120-mesh sieve for later use; add 9 times the amount of water to the dregs Decoct for 1 hour, filter, and combine the filtrate with the distilled aqueous solution for later use;

[0169] b. Add 5 parts of jujube, 1 part of licorice, 4 parts of water lily, 3 parts of ragwort, 2 parts of hollyhock seeds, 1.5 parts of rhubarb, 2 parts of poppy shell and decoct 3 times with 6 times the amount of Qiwei herbs , 1 hour each time, combine the decoction, filter, combine the filtrate with the standby solution, concentra...

Embodiment 3

[0173] a. Put 3 parts of peppermint, 3 parts of kaempferen, and 4 parts of chamomile into an extraction tank, add 12 times the amount of water to soak for 4 hours, extract volatile oil for 8 hours, and filter the distilled aqueous solution for later use. Collect volatile oil, use 5 g of β-cyclodextrin per 1 ml of volatile oil, stir at 30°C for 1 hour for inclusion, refrigerate overnight, filter with suction, dry at 40°C for 2 hours, grind finely, and pass through a 120-mesh sieve for later use; Add 12 times the amount of water to decoct for 1 hour, filter, and combine the filtrate with the distilled aqueous solution for later use;

[0174] b. Add 7 parts of jujube, 2 parts of licorice, 6 parts of water lily, 4 parts of ragwort, 3 parts of hollyhock seeds, 2 parts of rhubarb, 3 parts of poppy shell and decoct 3 times with 8 times the amount of Qiwei herbs , 1 hour each time, combine the decoction, filter, combine the filtrate with the standby solution, concentrate under reduced...

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PUM

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Abstract

The invention relates to an oral medicine Ganmao (zukamu) capsule, which is soaked in water with mint, kaempferen, and chamomile to extract volatile oil, and the distilled aqueous solution is filtered for later use, and the volatile oil is collected and encapsulated with β-cyclodextrin , refrigerated overnight, suction filtered, dried, ground, and sieved for later use; the dregs of the medicine were decocted with water, filtered, and the filtrate was combined with the distilled aqueous solution for later use; Caizi, rhubarb, and poppy husk are decocted with water, the decoction is combined, filtered, the filtrate is combined with the reserve liquid, concentrated under reduced pressure, ethanol is added, left standing, filtered, the filtrate is concentrated under reduced pressure, and the concentrated solution is prepared by spray drying Extract powder, add clathrate and mix evenly, add auxiliary material of microcrystalline cellulose starch, granulate, dry at low temperature, granulate, add micropowder silica gel, mix evenly, fill, and you can get Zukamu capsule; 172 patients with colds and influenza were treated with Zukamu capsules orally, and the total cure rate was 85.2%.

Description

technical field [0001] The present invention relates to a medicine cold (Uighur medical name is Zukamu) capsule and its preparation method and application, the medicine is used for treating cold and influenza Background technique [0002] Colds and influenza are common and frequently-occurring diseases that endanger people's health. They can cause fever, headache, nasal congestion, cough, runny nose, congested throat, sneezing, and sore limbs. Uyghur medicine has unique treatment methods in the treatment of colds and influenza. The original dosage form of Zukamu is granules, the dosage is large, 12 grams at a time, three times a day, and it contains more sucrose, which is restricted for many elderly people and patients who are forbidden from sugar. process, but there is no inclusion, and the volatile oil is still volatilized, so there is no volatile oil in the finished product, which affects the effectiveness of the drug. The quality standard of the dr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61P31/00
Inventor 哈木拉提·吾甫尔斯拉甫·艾白阿不都热依木·玉苏甫苏来满
Owner XINJIANG CICONHABO UYGUR MEDICINE