Photoacoustic removal for occlusions from blood vessels

A technique for blockages, blood vessels in the field of removing blood clots in human brain vessels

Inactive Publication Date: 2001-01-31
RGT UNIV OF CALIFORNIA +1
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  • Abstract
  • Description
  • Claims
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  • Photoacoustic removal for occlusions from blood vessels
  • Photoacoustic removal for occlusions from blood vessels
  • Photoacoustic removal for occlusions from blood vessels

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Embodiment Construction

[0029] Detailed description of preferred embodiments

[0030] Generally speaking, the present invention can be applied to the removal of substances that form partial or complete blockages in any human blood vessels, but the present invention is particularly aimed at opening up blood vessels where blood flow is completely or substantially blocked. More specifically, the preferred embodiment of the present invention is directed to removing clots from blood vessels in the brain that have caused ischemic stroke. If the blood flow in the blood vessel is restored within a few hours after the stroke, permanent damage to the blocked blood vessel can be avoided.

[0031] Before applying the technology of the present invention to patients with stroke symptoms, the physician firstly determines whether the stroke is caused by hemorrhage or cerebral vascular obstruction. This is usually judged by using standard computed tomography (CT) X-ray inspection. If the CT test determines...

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Abstract

Partial or total occlusions of fluid passages within the human body are removed by positioning an array of optical fibers in the passage and directing treatment radiation pulses along the fibers, one at a time, to generate a shock wave and hydrodynamic flows that strike and emulsify the occlusions. A preferred application is the removal of blood clots (thrombi and emboli) from small cerebral vessels to reverse the effects of an ischemic stroke. The operating parameters and techniques are chosen to minimize the amount of heating of the fragile cerebral vessel walls occurring during this photoacoustic treatment. One such technique is the optical monitoring of the existence of hydrodynamic flow generating vapor bubbles when they are expected to occur and stopping the heat generating pulses propagated along an optical fiber that is not generating such bubbles.

Description

[0001] U.S. government rights [0002] The U.S. government has the rights to the present invention under Contract W-7405-ENG-48 between the U.S. Department of Energy and the University of California to operate the Lawrence Livermore National Laboratory. Background of the invention [0003] Generally speaking, the present invention relates to the removal of partial or complete blockages in blood vessels by generating pressure waves in blood vessels through optical fiber media. More specifically, the present invention relates to removing blood clots in human brain vessels. Here, the term "clot" ("clot") refers to a thrombus, embolus, or some other complete blockage in a blood vessel. [0004] There are some medical methods available to open up partially or completely blocked blood vessels. For a long time, angioplasty (angioplasty) has been used to restore the complete blood flow in the coronary arteries for a long time by mechanically changing the shape of the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/20A61B18/22A61B17/22A61B18/24A61N5/06
CPCA61B18/245A61B2018/2211A61B2018/2095A61B2018/20359
Inventor 史蒂文·R·维苏里卢依兹·B·达西尔瓦彼得·M·塞利尔斯理查德·A·伦敦邓肯·J·梅特兰维克托·C·埃施
Owner RGT UNIV OF CALIFORNIA
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