Unlock instant, AI-driven research and patent intelligence for your innovation.

Healthy product raw liquor of armilariella tabescens for strengthening the body and protecting the liver and method for improving the formulation of armilariella tabescens

A technology for health care products and brightening bacteria, which is applied in the fields of bioengineering technology and pharmaceutical technology, can solve the problems of inability to achieve industrialized large-scale production, difficult to industrialized-scale production, large dosage of oral liquid, etc., so as to improve the prevention and treatment of chemical liver damage. , The effect of preparing many dosage forms and long shelf life

Inactive Publication Date: 2007-08-01
SICHUAN UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] But the obvious problems are: 1. Industrialized large-scale production cannot be realized by solid-state fermentation
At present, the cultivation of microorganisms with solid medium can only be carried out in 750 ml strain bottle, the cultivation time is long, and it is difficult to form industrial scale production
2. In terms of product dosage form, there are no other related dosage forms except Liangjun oral liquid, but the oral liquid has the disadvantages of large dosage, short storage period, and inconvenient transportation.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Healthy product raw liquor of armilariella tabescens for strengthening the body and protecting the liver and method for improving the formulation of armilariella tabescens
  • Healthy product raw liquor of armilariella tabescens for strengthening the body and protecting the liver and method for improving the formulation of armilariella tabescens

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0041] Preparation of Leucobacteria stock solution

[0042] 1. The strains used are the strains [Armillariella tabescens (Scop.ex Fr.) Sing] from Beijing Microorganism Culture Collection Center

[0043] 2. Bacteria slant culture: Aseptically inoculate the purchased strains on a PDA slant, and put them into a 28°C incubator for 10-15 days.

[0044] 3. Preparation of shake flask liquid seeds: cut the cultured slant strains and inoculate them into 250ml or 500ml Erlenmeyer flasks filled with liquid medium, place them in a shaker at 28°C and 140rpm and culture them in the dark for 7 days. The above-mentioned liquid seed medium is: 20% of potato juice, 2% of glucose, 0.3% of potassium dihydrogen phosphate, 0.15% of magnesium sulfate, V b1 A small amount, pH6.0.

[0045] 4. Bright bacteria fermentation: inoculate the liquid seeds with 10% of the inoculum amount of the fermentation medium, and place them on a shaker at 24° C. and 140 rpm for 6 days. The fermentation medium is: glu...

example 2

[0049] Preparation of Liangjun Granules

[0050] 20% starch, 20% dextrin, 10% sucrose powder and other auxiliary materials are added to the stock solution, and after mixing, the above slurry is spray-dried. The inlet temperature of spray drying is 110-150°C, and the outlet temperature is 50-60°C. Sieve through 40-60 mesh, pack separately. The main technical indicators are as follows:

[0051] Effective polysaccharide 22.1%, protein 15.6%, polypeptide 11.3%, moisture 4.3%.

example 3

[0053] Preparation of Leucobacteria Tablets

[0054] Concentrate the bright bacteria stock solution to 1 / 10, add 75% three-fold ethanol to precipitate overnight, collect the precipitate, and wash it successively with acetone and ether to obtain a dry powder. According to the weight ratio, 40% of Leucobacteria powder, 30% of starch, 20% of dextrin, and 10% of sucrose are mixed evenly, and 95% ethanol is used as a wetting agent, passed through a 20-mesh sieve to make wet granules, and dried in an oven at 60°C until the moisture content is 5%. , Whole grain 20 mesh, add 3% talcum powder and compress into tablets. Each piece weighs 0.4g. The main technical indicators of the product are as follows:

[0055] Effective polysaccharide 26.5%, protein 17.8%, polypeptide 12.1%, moisture 4.1%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a health product raw liquor of armilariella tabescens for strengthening the body and protecting the liver and method for improving the formulation of armilariella tabescens, which comprises bacterial inclined-plane cultivating, liquid seed cultivating and expanded fermentation.

Description

technical field [0001] The invention relates to a method for improving the dosage form of bright bacteria by using the raw liquid of bright bacteria strengthening liver and health care products, and belongs to the field of bioengineering technology and pharmaceutical technology. Background technique [0002] With the development of industry, the environment that human beings rely on for survival has also been seriously polluted. Many organic substances have serious harm to various organs of the human body. For example, various artificial boards, adhesives, wallpapers, etc. contain formaldehyde. Recognized as a potential carcinogen, it irritates the mucous membranes of the eyes and respiratory tract, etc., and eventually causes immune dysfunction, liver damage, lung damage, and nervous central system. In addition, alcoholic liver disease has also reached a level that cannot be ignored in my country in recent years. Alcohol damages organs, especially the liver. There are more t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/14A61K36/06A61K9/14A61K9/20A61K9/48A61P1/16A61K35/74
Inventor 孙启玲高婷白家峰何晨陈智陈咏竹
Owner SICHUAN UNIV