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Ophthalmic drug delivery device

A release device, drug technology, applied in the field of implants, can solve the problems of increased blood flow of choroidal hyperemia, increased bleeding and accumulation of subretinal fluid

Inactive Publication Date: 2002-10-23
ALCON INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent application reveals that this pressure increases choroidal hyperemia and blood flow through the subretinal neovascularization membrane, which in turn increases hemorrhage and accumulation of subretinal fluid

Method used

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  • Ophthalmic drug delivery device
  • Ophthalmic drug delivery device
  • Ophthalmic drug delivery device

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Embodiment Construction

[0035] The preferred embodiment of the present invention and its advantages can be attached by reference Figure 1 to Figure 21 To get the best understanding, the same reference signs will be used on the same or corresponding parts in the various figures.

[0036] figure 1 Figure 6 illustrates the parts of the human eye that are important for understanding the present invention. See figure 1 , Which schematically shows the human eye 90. The eye 90 has a cornea 92, a lens 93, a vitreous body 95, a sclera 100, a choroid 99, a retina 97, and an optic nerve 96. The eye 90 is generally divided into a front 89 and a back 88. The front portion 89 of the eye 90 includes the portion of the eye 90 in front of the serrated edge 11. The posterior portion 88 of the eye 90 generally includes the portion of the eye 90 behind the serrated edge 11. The retina 97 is actually connected to the choroid 99 in a circumferential manner near the ciliary ring 13 and behind the optic disc 19. The retina 97...

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Abstract

The present invention relates to a drug release device for the human eye. The human eye has a sclera, an inferior oblique muscle, and a macula. The device of the present invention includes a pharmaceutically active agent, and a geometry that facilitates implanting the device on an outer surface of the sclera, below the inferior oblique muscle, and deploying the pharmaceutically active agent to the macula above. Also disclosed is a method of delivering a pharmaceutically active agent to the back of the human eye.

Description

[0001] This application requires the rights and interests of a U.S. provisional application with the serial number 60 / 160,673, the filing date of October 21, 1999, and the name "drug release device", which has been included in this specification. Technical field [0002] The present invention generally relates to implants with biocompatibility for the local release of active pharmaceutical agents into body tissues. More specifically, but not limiting, the present invention relates to biocompatible implants for local delivery of pharmaceutically active agents to the back of the eye. Background technique [0003] Several diseases at the back of the eye threaten vision. Age-related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathy (such as diabetic retinopathy, vitreoretinopathy), retinitis (such as cytomegalovirus retinitis (CMV)), pigment layer Inflammation, macular edema, glaucoma, and neuropathy are a few examples of these diseases. [0004] Age-related...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61F9/00A61F9/007A61K9/00
CPCA61F9/0017A61F9/00781A61K9/0051A61F2/14A61F2009/00891A61F2250/0067
Inventor 约瑟夫·雅各比
Owner ALCON INC
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