Mouth cavity fast disintegrating tablet of Chinese medicine or natural medical matters and its preparing method

An oral fast disintegrating tablet, a natural source technology, applied in the field of oral fast disintegrating tablet of traditional Chinese medicine or natural source medicinal substance and its preparation, can solve problems such as poor disintegration performance, achieve good fast disintegrating and fast dissolving performance, fast drug dissolution, Well-formulated effect

Inactive Publication Date: 2004-02-11
NINGBO LIWAH PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The technical problem to be solved by the present invention is to overcome the disadvantages of poor disintegration performance of existing traditional Chinese medicine tablets, and provide a kind of oral fast-disintegrating tablet of traditional Chinese medicine or natural source medicinal substance and its preparation method

Method used

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  • Mouth cavity fast disintegrating tablet of Chinese medicine or natural medical matters and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0025] Huang Yangning Orally Disintegrating Tablets

[0026] Recipe: (1000 tablets)

[0027] Cyclovitamin D 1.0g or 2.0g

[0028] Lactose 150g

[0029] Mannitol 50g

[0030] Low-substituted hydroxypropyl cellulose 18g

[0031] Stevioside 10g

[0032] 5% ethyl cellulose ethanol solution 100ml

[0033] Sweet orange essence 8g

[0034] Magnesium Stearate 4g

[0035] Preparation:

[0036]1. Pulverize and sieve: pulverize the cyclovir buxicine D and part of the lactose in the prescription through a 200-mesh sieve, and pulverize the remaining components through a 100-mesh sieve, and store them separately for future use.

[0037] 2. Preparation of double powder: Take the prescribed amount of Huowei buxicine D and 49g of 200 mesh lactose fine powder, and use the method of equal-volume incremental dilution to fully mix and make a 50-fold powder for later use.

[0038] 3. Mixing: Lactose fine powder, mannitol, stevioside, internally added...

Embodiment approach 2

[0046] Yixinketone (hawthorn leaf extract) orally disintegrating tablets:

[0047] Recipe: (1000 tablets)

[0048] Hawthorn Leaf Extract* 32g

[0049] Mannitol 40g

[0050] Taurine 30g

[0051] Microcrystalline Cellulose 130g

[0052] Croscarmellose 18g

[0053] Pineapple essence 110g

[0054] Aspartame 10g

[0055] 5-10% PVP K30 Solution 100ml

[0056] Magnesium Stearate 4g

[0057] *Hawthorn leaf extract: It can be adjusted appropriately according to the total flavonoid content in the extract (calculated by anhydrous rutin), but it must be ensured that the flavonoids in each tablet are not less than 25mg (calculated by anhydrous rutin).

[0058] Preparation:

[0059] 1. Crush and sieve: Grind the hawthorn leaf extract and various auxiliary materials in the prescription separately and pass through a sieve of more than 100 meshes, and store the fine powder separately for later use.

[0060] 2. Mixing: In addition to...

Embodiment approach 3

[0067] Ginkgo Biloba Extract Orally Disintegrating Tablets

[0068] Recipe: (1000 tablets)

[0069] Ginkgo biloba extract* 40g

[0070] Mannitol 42g

[0071] Taurine 35g

[0072] Microcrystalline Cellulose 32g

[0073] Crospovidone 10g

[0074] Sodium saccharin 8g

[0075] Sweet orange essence 10g

[0076] 5% PVP K30 Solution 100ml

[0077] Magnesium Stearate 4g

[0078] *Ginkgo biloba extract: flavonoids ≥ 24%, ginkgolides ≥ 6%, the amount of extract can be adjusted according to the content of flavonoids, but the total flavonoids contained in each tablet should not be less than 9.6mg.

[0079] Preparation:

[0080] 1. Pulverize and sieve: Ginkgo biloba extract and various excipients in the prescription are pulverized and sieved over 100 meshes, and the fine powders are stored separately for later use.

[0081] 2. Mixing: Except for the added part of croscarmellose sodium and magnesium stearate, weigh other materials acco...

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Abstract

The present invention relates to a kind of oral cavity fast disintegrating tablet of Chinese medicine or natural medicine, and the cavity fast disintegrating tablet comprises active component of Chinese medicine or natural medicine and medicinal applicable supplementary material. The active component of Chinese medicine or natural medicine is compound separated from Chinese medicine or natural medicine plant. The oral cavity fast disintegrating tablet can dissolve in oral cavity fast, in 40 sec, without needing water drunk, has no foreign matter feeling and may be leached in 15 min. The oral cavity fast disintegrating tablet may be produced with common tablet press.

Description

technical field [0001] The invention relates to a traditional Chinese medicine tablet, in particular to an orally rapidly disintegrating tablet made of traditional Chinese medicine or natural medicinal plant active ingredients or extracts containing active ingredients and a preparation method thereof. Background technique [0002] It has been thousands of years in China and some countries and regions in the world to use some therapeutic substances derived from plants and animals to treat diseases. China has thus formed a unique medical system—Chinese medicine and Pharmacy. The important role and significance of traditional Chinese medicine in disease prevention and treatment have been recognized. In the initial stage, traditional Chinese medicine is taken in the original form, that is, the single Chinese herbal medicine or the compound Chinese herbal medicine is decocted in water, or the Chinese herbal medicine is ground into fine powder and taken directly. With the advanc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/57A61K47/38
Inventor 刘辉
Owner NINGBO LIWAH PHARM CO LTD
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