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Medicinal compsns.

A composition and drug technology, applied in the directions of drug combination, drug delivery, antipyretic drugs, etc., can solve the problems of physical exhaustion, poor expectorant effect, unsatisfactory and the like

Inactive Publication Date: 2004-08-11
SS PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the expectorant drugs with expectorant effect added to conventional cold medicine compositions have poor expectorant effect and are unsatisfactory.
[0004] Phlegm sticks to the throat, causing pain to cold patients and exhausting their physical strength, so it is necessary to develop pharmaceutical compositions such as cold medicines with better expectorant effects

Method used

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  • Medicinal compsns.

Examples

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Comparison scheme
Effect test

preparation example Construction

[0024] The pharmaceutical composition of the present invention is prepared by properly combining the above-mentioned ingredients and pharmaceutically acceptable additives, and making them into solid, semi-solid or liquid preparations for oral administration such as tablets, granules, microgranules, Powder, capsule, soft capsule, pill, suspension, emulsion, liquid preparation for internal administration, syrup or dry syrup, etc. It is also possible to make the pharmaceutical ingredients into microparticles, such as microcapsules, nanocapsules, microspheres or nanospheres, etc. before preparing the above preparations.

[0025] There is no particular limitation on the method for preparing the pharmaceutical composition of the present invention, and various methods can be used. For example, when it is necessary to prepare granular powder for formulations such as tablets, granules, granules, powders, capsules, pills or dry syrups, conventional granulation methods can be used, and e...

Embodiment 1

[0080] tablet:

[0081] Fudosteine ​​(200 g), ibuprofen (75 g), corn starch (33 g), talc (1 g) and magnesium stearate (1 g) were prepared into a powder for tableting by a conventional method. The obtained powder was tableted using a rotary tablet machine to prepare tablets each having a diameter of 9 mm and a weight of 310 mg.

Embodiment 2

[0083] tablet:

[0084] Fudosteine ​​(133.3 g), acetaminophen (100 g), potato starch (44.7 g), talc (1 g) and magnesium stearate (1 g) were prepared into a powder for tableting by a conventional method. The resulting powder was tableted using a rotary tablet press, whereby tablets each having a diameter of 8.5 mm and a weight of 280 mg were prepared.

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PUM

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Abstract

Medicinal compositions characterized by containing fudosteine and an antipyretic / analgesic. These medicinal compositions are medicinal compositions to be used for common cold, etc. which have improved sputum-removal and antiinflammatory effects.

Description

technical field [0001] The present invention relates to a pharmaceutical composition, and more particularly, the present invention relates to a pharmaceutical composition having excellent expectorant and anti-inflammatory effects, which can be advantageously used as a medicine for colds and the like. Background technique [0002] Conventionally, many medicinal compositions for colds have been commercialized. In order to achieve the purpose of suppressing or relieving cold symptoms, some other ingredients are usually added in addition to the antipyretic / analgesic to this type of composition. [0003] For example, when inflammation such as bronchitis is caused by a cold, symptoms such as cough and profuse phlegm are often present, so medicinal ingredients having an expectorant effect can be added to the medicinal composition for colds. However, the expectorant drugs with expectorant effect added to conventional cold medicine compositions have poor expectorant effect and are u...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K9/16A61K9/20A61K9/28A61K9/48A61K31/166A61K31/167A61K31/192A61K31/198A61K31/4152A61K31/609A61K31/616A61K31/618A61K47/18A61P11/00A61P11/10A61P29/00
CPCA61K9/1652A61K9/2866A61K31/192A61K31/198A61K31/616A61K31/167A61K31/609A61K9/2826A61K31/618A61K9/2059A61K31/4152A61K31/166A61K9/0095A61P11/00A61P11/10A61P29/00A61P31/00A61K2300/00
Inventor 小贯洋一冈田实坂井裕贵神户英芳水野博之今森胜美
Owner SS PHARMA CO LTD
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