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Sustained releasing breviscapine tablets

A technology of breviscapine and sustained-release tablets, which is applied in the field of medicine, can solve the problems of large fluctuation of blood drug concentration, unsatisfactory clinical application, and many times of taking, etc., and achieves a short development cycle, reduces the incidence of adverse reactions, High bioavailability effect

Inactive Publication Date: 2004-09-22
NANJING CHANGAO PHARMA SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The number of times of taking is high, the blood concentration fluctuates greatly, and there is a certain incidence of adverse drug reactions, so the clinical application is not ideal

Method used

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  • Sustained releasing breviscapine tablets
  • Sustained releasing breviscapine tablets
  • Sustained releasing breviscapine tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] scutellarin

[0031] figure 1 It is the in vitro release curve of the scutellarin sustained-release tablet obtained in Example 1.

Embodiment 2

[0033] scutellarin

[0034] time in hours

[0035] figure 2 It is the in vitro release curve of the scutellarin sustained-release tablet obtained in Example 2.

Embodiment 3

[0037] scutellarin

[0038] time in hours

[0039] image 3 It is the in vitro release curve of the scutellarin sustained-release tablet obtained in Example 3.

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Abstract

A slow-releasing breviscapine B tablet for treating apoplexy sequela, palsy, cerebral thrombosis, coronary heart disease, angina pectoris, myocardial infarction, and rheumatalgia is prepared from breviscapine B, cellulose ether and / or cellulose ester or cross-linked polyacrylic resin, and assistant. Its advantage is high curative effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to Chinese herbal medicine preparation technology. Background technique [0002] Erigeron breviscapus (Erigeron breviscapus), also known as Erigeron breviscapus, is a short-stem flying canopy. It is the whole plant of Erigron breviscapus (vaniot) Hand Mazz of Compositae. The whole herb or root is used as medicine. Perennial herb, 10-40CM high, with flowers like Dengzhan and roots like Asarum, hence the name. Born in mountain sparse forests, grass and sunny slopes, distributed in Sichuan, Yunnan and other provinces. Harvest and wash when the flowers with lush stems and leaves bloom in autumn, and use fresh or dry for later use. As a commonly used herbal medicine, it was first recorded in "Southern Yunnan Materia Medica" in the Ming Dynasty, and was included in the "Pharmacopoeia of the People's Republic of China" in 1977 due to its good curative effect. ...

Claims

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Application Information

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IPC IPC(8): A61K9/22A61K31/7048A61P9/10
Inventor 陈静李战晁阳沈飞黄海燕
Owner NANJING CHANGAO PHARMA SCI & TECH CO LTD
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