Clindamycin metronidazole vagina effervescent tablet and its preparing method and use

A technology of clindamycin and metronidazole, which is used in pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, etc., can solve the problem that drugs cannot fully reach the vagina, affect the effect of drug treatment, and the foam is not long-lasting. and other problems, to achieve the effect of favorable drug distribution, easy normal activities, and large foaming volume
CN1586497AInactive Publication Date: 2005-03-02η¨‹ζœˆε‘ +1
2 Cites 15 Cited by

Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
η¨‹ζœˆε‘
Publication Date
2005-03-02
Estimated Expiration
Not applicable Β· inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The vagina effervescent tablet has the salt or ester of clindamycin and metronidazole as active component and is prepared via a common tablet making process. The present invention features that the said effervescent tablet contains hydroxypropyl methyl cellulose as adhesive. Compared with conventional effervescent tablet, the present invention has the advantages of greater foam amount, fine and lasting foams, homogeneous distribution of effective medicine component, long duration, raised medicine curative effect, simple preparation process, stable quality and being suitable for industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

Technical field:

[0001] The invention relates to a clindamycin compound, a clindamycin-metronidazole vaginal effervescent tablet, a preparation method thereof and an application in medical treatment. Background technique:

[0002] Clindamycin is a lincomycin antibiotic with strong antibacterial activity and broad antibacterial spectrum. It has obvious antibacterial effect, and also has bactericidal effect on most anaerobic bacteria, chlamydia, mycoplasma, Plasmodium falciparum and Toxoplasma gondii. This product acts on the 50S subunit of the ribosome of sensitive bacteria to prevent the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. Clindamycin is generally a bacteriostatic drug, but it also has a bactericidal effect on highly sensitive bacteria at high concentrations. It is widely used clinically to treat infections caused by aerobic gram-positive bacteria and various anaerobic bacteria.

[0003] Metronidazole is a metronida...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More