Fibrauretine-amino acid fluid for transfusion and its production process

A technology of dapatine and amino acid, which is applied in the field of amino acid infusion to achieve the effect of stable, reliable and convenient operation of the product

Inactive Publication Date: 2005-04-27
KUNMING ZIJIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing amino acid infusion can only be used as a nutritional support or supplement, and critically ill patients are often severely infected, and must be infused with necessary anti-infective drugs at the same time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, produce eight kinds of amino acid transfusions of rhubarb, prescription (1000ml):

[0028] Rhubarb 0.08g L-Isoleucine 3.82g

[0029] L-Leucine 5.03g L-Lysine Acetate 4.52g

[0030] L-Methionine 2.34g L-Phenylalanine 5.65g

[0031] L-Threonine 2.78g L-Tryptophan 1.0g

[0032] L-Valine 3.98g Mannitol 70g

[0033] Preparation process: under the condition of 10,000 grade and nitrogen protection, first dissolve a small amount of L-tryptophan in ~20ml water for injection, and pay attention to make it completely dissolved, dissolve chrysophanin in ~20ml water for injection, and Take care to dissolve completely. Then dissolve other amino acids in ~500ml water for injection, add the above dissolved tryptophan solution and emodin solution, add mannitol and dilute it to the required volume ~800ml with water for injection, add antioxidant, adjust isotonicity, supplement Add water for injection to the final desired volume. Filtration, the filtrate is treated with...

Embodiment 2

[0034] Embodiment 2, produce chrysanthemum ten kinds of amino acid transfusions, formula (1000ml):

[0035] Rhubarb 0.20g L-Isoleucine 3.72g

[0036] L-Leucine 5.00g L-Lysine Acetate 4.32g

[0037] L-Methionine 2.30g L-Phenylalanine 5.60g

[0038] L-Threonine 2.71g L-Tryptophan 0.90g

[0039] L-Valine 3.98g L-Arginine Hydrochloride 5.10g

[0040] L-Tyrosine 0.27g L-Histidine 2.10g

[0041] Sorbitol 60g

[0042] Preparation process: with embodiment 1 (omitted). Can make 2 bottles of 500ml: 100mg chrysophanin eleven kinds of amino acid infusion finished products.

Embodiment 3

[0043] Embodiment 3, produce chrysanthemum eighteen kinds of amino acid transfusions, prescription (1000ml):

[0044] Rhubarb 0.40g L-Isoleucine 3.52g

[0045] L-Leucine 4.80g L-Lysine Acetate 4.12g

[0046] L-Methionine 2.10g L-Phenylalanine 5.22g

[0047] L-Threonine 2.40g L-Tryptophan 0.80g

[0048] L-Valine 3.63g L-Arginine Hydrochloride 4.90g

[0049] L-Tyrosine 0.24g L-Histidine 2.00g

[0050] L-Alanine 1.95g L-Proline 1.00g

[0051] L-Serine 1.00g Glycine 7.56g

[0052] L-Cystine 0.10g L-Glutamic Acid 0.75g

[0053] L-Aspartic Acid 2.50g Sorbitol 50.00g

[0054] Preparation process: with embodiment 1 (omitted). Two bottles of rheumin 18 kinds of amino acid infusion products with specifications of 500ml: 200mg can be prepared.

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PUM

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Abstract

The present invention provides one kind of fibrrauretine-amino acid fluid for transfusion and features that each bottle of medicine contains fibrrauretine in 0.02-0.50 g, amino acid 25-60 g, auxiliary medicine 0-10 g and medicinal supplementary material. The present invention may be used a tonic for preventing and treating diseases and may be also injected to patient after some essential treating medicines are added to result in both treating and nourishing effects. Experiment shows that the present invention has high stability, no irritation, and certain antibiotic and antiphlogistic effect.

Description

technical field [0001] The invention relates to an amino acid infusion solution, in particular to an emodin amino acid infusion solution containing bioactive drugs. Background technique [0002] Rhubarb (also known as Huangtengsu, Fibranine, Palmitine Hydrochloride, Palmatine Hydrochloride, Palmatine) is a plant antibiotic unearthed from Pingbian Miao Autonomous County in Yunnan Province during 1970-1972, when it was promoting Chinese herbal medicine. The original medicinal material - the Phantasmalaceae plant Huangteng [Fibraureatinctoria Lour.] is used in the folk for dyeing cloth, trauma infection and chronic ulcers caused by sores. There are two types of chrysophanin, tablets and water injections, which belong to heat-clearing and detoxifying drugs, and have the effect of enhancing the phagocytosis of white blood cells. For the treatment of gynecological inflammation, surgical infection, bacillary dysentery, enteritis, respiratory tract and urinary tract infection, conj...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/14A61K31/195A61P1/00A61P11/00A61P13/02A61P15/00A61P17/02A61P27/02A61P31/04
Inventor 于军
Owner KUNMING ZIJIAN BIOTECH
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