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Chinese medicine composition for treating dermatosis and its preparing method

A composition and technology for skin diseases, applied in skin diseases, drug combinations, pharmaceutical formulations and other directions, can solve the problems of large dosage, low bioavailability, inconvenient taking, carrying, storage and transportation, etc. powerful effect

Inactive Publication Date: 2005-10-19
广东怡康制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And the disintegration time of the pill is long, the bioavailability is low, and the dosage is large (3.6g each time), which causes inconveniences such as taking, carrying, storage and transportation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 Capsule preparation of Chinese medicine composition of the present invention

[0021] a) Weigh 40g madder, 20g snake slough, 40g nepeta ear (charcoal), 40g peach kernel, 40g red peony root, 40g angelica, 80g rhizoma rhizome, 40g Kochia chinensis, 40g cocklebur (stir-fried), 40g rehmannia glutinosa , Forsythia 40g, Honeysuckle 40g, Kudiding 40g, Smilax tuckahoe 40g, Phellodendron 20g, Saponaria thorn 40g, Campanulaceae 40g, Motherwort 40g, Bitter almond (peeled and fried) 40g, Fangfeng 20g, Chi Fuling 80g, White peony root 40g , 20g of cicada slough, 40g of burdock, 40g of peony bark, 40g of white fresh bark, 40g of rehmannia glutinosa, 40g of rhubarb (stir-fried with wine), 40g of honeysuckle, 20g of comfrey, 40g of fritillaria, 20g of Chuanxiong (wine moxibustion), 40g of licorice , 20g of Angelica dahurica, 40g of geranium seeds, 20g of Bauhinia bark, 40g of Caulis Spatholobus, 20g of duckweed, 20g of safflower, set aside;

[0022] b) Combine the madder,...

Embodiment 2

[0025] The tablet preparation of embodiment 2 Chinese medicine composition of the present invention

[0026]It is basically the same as Example 1, the difference is that in step d) the above-mentioned filtrate 1 and filtrate 2 are combined, concentrated under reduced pressure to a relative density of 1.10-1.15 (60°C), and then spray-dried, take spray powder, add appropriate amount of auxiliary materials, and prepare The granules are then compressed into 1000 tablets, each weighing 0.52g.

[0027] The taking method and dosage of the above-mentioned capsules or tablets: take orally, 2 capsules (tablets) each time, twice a day.

experiment example 1

[0028] Experimental Example 1 Effect of ethanol concentration on dry extract yield and arctiin transfer rate

[0029] Experimental method: get medical material and be divided into 5 groups, each group a prescription amount (pill) 390g altogether, add the ethanol (55%, 65%, 75%, 85%, 95% of 11 (4,4,3) times of different concentrations respectively ), reflux extraction 3 times, 1.5 hours each time for the 1st and 2nd times, 1 hour for the 3rd time; merge, filter, weigh, take samples to determine the content of arctiin and its solid content, and calculate, the experimental results are shown in Table 1:

[0030] Experiment number

[0031] The above experimental results show that: when the ethanol concentration is 55% to 75%, the transfer rate of arctiin is the highest, and the transfer rate of arctiin decreases when the ethanol concentration is greater than 75%. Therefore, the preferred ethanol concentration is: 55%-75%, and the optimum ethanol concentration is 65%.

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PUM

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Abstract

The present invention discloses a kind of Chinese medicine composition for treating dermatosis and its preparation process. The Chinese medicine composition consists of alcohol extract of 16 kinds of Chinese medicinal materials, including madder, snake slough, etc.; the water extract of 23 kinds of Chinese medicinal materials, including cogongrass rhizome, broom cypress fruit, etc. and proper amount of communication supplementary material. The preparation process includes weighing material; alcohol reflux extracting the 16 kinds of Chinese medicinal materials and filtering to obtain the first filtrate; twice decocting the 23 kinds of Chinese medicinal materials and filtering to obtain the second filtrate; merging the first filtrate and the second filtrate, concentrating, drying to obtain medicine powder; adding supplementary material, pelletizing, and final tabletting or encapsulating.

Description

technical field [0001] The invention relates to a medicine for treating skin diseases, in particular to a traditional Chinese medicine composition for treating skin diseases, and also relates to a preparation method of the Chinese medicine composition. Background technique [0002] Traditional Chinese medicine believes that skin diseases are due to the presence of blood heat in the blood, and the poison in the blood is caused by the accumulation of heat in the five internal organs, which is injected into the blood and fights with the blood, causing the blood to be unclear and turbid. In addition, the blood and qi in the meridians are not in harmony, and external dampness and heat damage the blood of the human body, resulting in dry blood, resulting in poor nourishment of the skin, resulting in unclean skin, which seriously affects the beauty of human skin, especially the beauty of facial skin. [0003] Tongrentang's Xuedu Pill for Dermatitis follows the experience of Dr. Shi...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/48A61K35/583A61K35/64A61P17/00A61P17/10
Inventor 陈小坚卢竹丽
Owner 广东怡康制药有限公司
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