Colchicines microcapsule and preparation method

Abstract

A microsoftgel of colcin and its preparing process are disclosed. It can be used to prepare any taget medicine by proportionally mixing it with medicinal auxiliary for higher stability and bioactivity and low irritation to stomach and intestine.

Description

technical field

[0001] The invention relates to a colchicine microcapsule with significant analgesic and anti-inflammatory effects on gout and a production method thereof. Background technique

[0002] When metabolic enzymes in the body are deficient and purines are synthesized too much, excessive uric acid will appear in the blood. Due to the low solubility of uric acid, it is easy to crystallize and precipitate in the joint cavity, connective tissue and kidneys, etc., causing cell phagocytosis and degranulation, lysozyme The body releases various decomposing enzymes, and produces inflammatory mediators such as histamine and slow-release peptides locally in the human body, causing gouty arthritis and kidney stones and other diseases. Colchicine is produced from the bulbs of Liliaceae plants, Colchicum autumnale L., Lilium brownii F.E. Brownvar. cokchesteri Wils, bulbs, stems, leaves, seeds, etc. Extract the isolated alkaloids. The colchicine included in the Chinese Pharma...