Freezedrying type vaccine of AIDS recombined poxvirus with Ankara gene stock carrier, and preparation method

An Ankara strain and carrier vaccine technology, applied in the directions of antiviral agents, freeze-dried delivery, pharmaceutical formulations, etc., can solve problems such as no freeze-dried preparations, and achieve the effects of good stability, easy production and use, and low cost
CN1695737AInactive Publication Date: 2005-11-16JILIN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JILIN UNIV
Publication Date
2005-11-16
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

A freeze-dried carrier vaccine of HIV recombinant MVA virus features high stability. It is prepared from the liquid-type carrier vaccine of HIV recombinant MVA virus through adding the protecting agent prepared from mycose, mannitol, dextran and inositol, stirring and vacuum freeze drying.
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Description

technical field

[0001] The invention belongs to the technical field of biological products, and in particular relates to the preparation of a freeze-dried formulation vaccine using recombinant MVA virus as an expression vector. Background technique

[0002] AIDS (HIV) is considered to be the first major infectious disease that directly threatens human health in the world. More than 95% of HIV infections occur in developing countries. So far, education and interventions in high-risk behaviors have only slowed the spread, not stopped it. High-efficiency antiviral therapy is expensive and too complicated for most infected people, and in addition, it cannot completely eliminate the virus from the body. In this case, only the AIDS vaccine can really effectively prevent and control AIDS. In particular, it is necessary to receive safe, highly immunogenic, and highly effective AIDS vaccines.

[0003] In recent years, the study of live vector vaccines has received more and more a...

Claims

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