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Method for preparing red sage formulation or buccal tablet for treating coronary disease

A technology for coronary heart disease and buccal tablets, which is applied in the field of drugs for the treatment of coronary heart disease, can solve problems such as slow absorption, and achieve the effects of fast onset, pain relief, and guaranteed therapeutic effect.

Inactive Publication Date: 2006-02-08
张佳翼
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although the above three ingredients work synergistically well, their absorption is slow

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] This example is Guanxin Danshen buccal tablet, which is prepared from the following raw materials, each tablet weighs 0.6 grams, and each tablet contains ginsenoside Rg1 (C 42 h 72 o 14 ) shall not be less than 6.8mg: Danshen 480g, Panax notoginseng 480g, balsamic oil 4.2ml.

[0031] The preparation method is as follows: reflux extraction of salvia miltiorrhiza with ethanol twice, 70 minutes each time, combine the extracts, filter, recover ethanol from the filtrate, concentrate to a clear paste with a relative density of about 1.10 (60°C), and set aside. Grind Panax notoginseng into coarse powder, extract twice with 70% ethanol under reflux, each time for 1.5 hours, combine the extracts, filter, recover ethanol from the filtrate, and concentrate to a clear paste with a relative density of 1.20-1.25 (measured at 60°C). Add an appropriate amount of diatomaceous earth, mix well, dry under reduced pressure at 80°C, crush into fine powder, add ethanol to reflux for extract...

Embodiment 2

[0036] The present embodiment is Guanxin Danshen Granules, which are prepared from the following raw materials, and the weight of each bag is 8 grams:

[0037] Main ingredients: Danshen 442g, Panax notoginseng 518g, balm oil 3.9ml.

[0038] The preparation method is as follows: reflux extraction of salvia miltiorrhiza with ethanol twice, 70 minutes each time, combine the extracts, filter, recover ethanol from the filtrate, concentrate to a clear paste with a relative density of about 1.10 (60°C), and set aside. Grind Panax notoginseng into coarse powder, extract twice with 70% ethanol under reflux, each time for 1.5 hours, combine the extracts, filter, recover ethanol from the filtrate, and concentrate to a clear paste with a relative density of 1.20-1.25 (measured at 60°C). Add an appropriate amount of diatomaceous earth, mix well, dry under reduced pressure at 80°C, crush into fine powder, add ethanol to reflux for extraction twice, each time for 1 hour, combine the extracts...

Embodiment 3

[0042] This embodiment is Guanxin Danshen Capsules, prepared from the following raw materials, each capsule has a weight of 0.6 grams, and each capsule contains ginsenoside R g1 (C 42 h 72 o 14 ) shall not be less than 6.8mg:

[0043] Main ingredients: Danshen 520g, Panax notoginseng 440g, balm oil 4.6ml.

[0044] The preparation method is as follows: reflux extraction of salvia miltiorrhiza with ethanol twice, 70 minutes each time, combine the extracts, filter, recover ethanol from the filtrate, concentrate to a clear paste with a relative density of about 1.10 (60°C), and set aside. Grind Panax notoginseng into coarse powder, extract twice with 70% ethanol under reflux, each time for 1.5 hours, combine the extracts, filter, recover ethanol from the filtrate, and concentrate to a clear paste with a relative density of 1.20-1.25 (measured at 60°C). Add an appropriate amount of diatomaceous earth, mix well, dry under reduced pressure at 80°C, crush into fine powder, add eth...

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Abstract

The invention discloses a salvia miltiorrhizae preparation for treating coronary disease, which is prepared from the following raw material (by weight ratio), salvia miltiorrhizae 440-520g, notoginseng 440-520g, rosewood oil 3.8-4.6ml.

Description

technical field [0001] The invention relates to a medicine for treating coronary heart disease. Background technique [0002] Coronary heart disease is the abbreviation of coronary atherosclerotic heart disease. The coronary artery supplies the heart's own blood. Severe atherosclerosis or spasm of the coronary artery causes the coronary artery to narrow or occlude. kind of heart disease. Its main clinical manifestations are angina pectoris and arrhythmia caused by myocardial ischemia and hypoxia. In severe cases, myocardial infarction may occur, resulting in extensive myocardial necrosis and life-threatening. Cardiovascular disease, as the "first killer" that endangers human health, has spread to the whole world and is the main disaster in many rich countries. By 1940, coronary heart disease was the leading cause of death in the United States and some industrialized countries. [0003] According to the data of 11 countries released by the World Health Organization in 1990...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/16A61K9/20A61K9/46A61K9/48A61P9/10
Inventor 张佳翼高尚
Owner 张佳翼
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